A benchmarking of pipelines for detecting ncRNAs from RNA-Seq data

S Di Bella, A La Ferlita, G Carapezza… - Briefings in …, 2020 - academic.oup.com
Next-Generation Sequencing (NGS) is a high-throughput technology widely applied to
genome sequencing and transcriptome profiling. RNA-Seq uses NGS to reveal RNA identities …

Robust design of microbial strains

…, G Carapezza, C Angione, P Lió, G Nicosia - …, 2012 - academic.oup.com
… For a set of L genetic manipulations, the GPR mappings are represented by a forumla matrix
G, where the forumla th element is 1 if the lth genetic manipulation maps onto the reaction j, …

[HTML][HTML] Multi-objective optimization of genome-scale metabolic models: the case of ethanol production

A Patané, G Jansen, P Conca, G Carapezza… - Annals of Operations …, 2019 - Springer
Ethanol is among the largest fermentation product used worldwide, accounting for more
than $$90\%$$ 90 % of all biofuel produced in the last decade. However current production …

Pareto optimal design for synthetic biology

…, J Costanza, G Carapezza, G Nicosia - IEEE transactions on …, 2015 - ieeexplore.ieee.org
Recent advances in synthetic biology call for robust, flexible and efficient in silico optimization
methodologies. We present a Pareto design approach for the bi-level optimization …

[HTML][HTML] Establishment and genomic characterization of the new chordoma cell line Chor-IN-1

…, L Cozzi, C Cusi, F Bozzi, N Beltrami, G Carapezza… - Scientific reports, 2017 - nature.com
… Giovanni Carapezza … Slides were G banded with Wright staining and analyzed at 100
X magnification with a Leica DM6000D microscope. … Giovanni Carapezza

[HTML][HTML] Multi-target analysis and design of mitochondrial metabolism

C Angione, J Costanza, G Carapezza, P Lió, G Nicosia - PloS one, 2015 - journals.plos.org
… In general, a constraint is a function g(x) that certificates if a solution for a given optimization
problem is feasible or not. We consider constraints defined as g(x): R n → R if g(x) ≤ θ, …

Multi-objective optimisation, sensitivity and robustness analysis in FBA modelling

…, G Carapezza, C Angione, P Liò, G Nicosia - … Methods in Systems …, 2012 - Springer
… where g is a vector of weights (n dimensional) associated with the synthetic objectives, and
g is its transpose. For example, when the synthetic objectives vj and vh have to be maximised…

Pareto optimality in organelle energy metabolism analysis

C Angione, G Carapezza, J Costanza… - … ACM transactions on …, 2013 - ieeexplore.ieee.org
… Giovanni Carapezza received the graduate degree in telecommunications engineering
from the University of Catania in July 2011 with a thesis entitled “Services and potentialities of …

Efficient behavior of photosynthetic organelles via Pareto optimality, identifiability, and sensitivity analysis

G Carapezza, R Umeton, J Costanza… - ACS synthetic …, 2013 - ACS Publications
In this work, we develop methodologies for analyzing and cross comparing metabolic models.
We investigate three important metabolic networks to discuss the complexity of biological …

Multi-objective optimization and analysis for the design space exploration of analog circuits and solar cells

A Patanè, A Santoro, P Conca, G Carapezza… - … Applications of Artificial …, 2017 - Elsevier
This paper introduces PareDA (ParetoDesignAutomation), a composite automated methodology
for the optimization of analog circuits and solar cell devices. The PareDA framework …