Legionella antibiotic susceptibility testing: is it time for international standardization and evidence-based guidance?

E Portal, G Descours, C Ginevra… - Journal of …, 2021 - academic.oup.com
Legionella pneumophila, a Gram-negative bacillus, is the causative agent of Legionnaire’s
disease, a form of severe community-acquired pneumonia. Infection can have high morbidity, …

Legionnaires' disease in France

C Campèse, G Descours, A Lepoutre, L Beraud… - Médecine et maladies …, 2015 - Elsevier
The aim of this review was to describe the current knowledge of Legionnaires’ disease (LD)
illustrated by the epidemiological situation in France in 2013. LD is a severe pneumonia …

[HTML][HTML] Macrolide-resistant Bordetella pertussis infection in newborn girl, France

S Guillot, G Descours, Y Gillet, J Etienne… - Emerging infectious …, 2012 - ncbi.nlm.nih.gov
… DNA sequencing and PCR–restriction fragment length polymorphism showed a 2047 A-to-G
mutation in the 3 copies of the 23S rRNA gene. Monitoring for macrolide resistance is …

Slowly or nonresolving Legionnaires' disease: case series and literature review

C Pouderoux, C Ginevra, G Descours… - Clinical Infectious …, 2020 - academic.oup.com
G less than 5 g/L, human immunodeficiency virus infection, or immunosuppressive (IS)
drugs. The following clinical data were recorded for primary and ulterior LD episodes: fever, …

Identification of Legionella in Clinical Samples

S Jarraud, G Descours, C Ginevra, G Lina… - Legionella: Methods and …, 2013 - Springer
… : Weigh 1.20 g NaCl, 0.04 g of MgSO 4 ⋅7H 2 O, 1.42 g of Na 2 HPO 4 and 1.36 g of KH 2
PO 4 , and bring the volume up to 100 mL with distilled water. Solution B: weigh 0.04 g of CaCl …

Legionella pneumophila sequence type 1/Paris pulsotype subtyping by spoligotyping

…, R Arquilliere, H Meugnier, G Descours… - Journal of clinical …, 2012 - Am Soc Microbiol
Endemic strains of Legionella pneumophila sequence type 1 (ST1), in particular the ST1/Paris
pulsotype, are dispersed worldwide and represent about 10% of culture-proven clinical …

Evaluation of the Accelerate Pheno™ system for rapid identification and antimicrobial susceptibility testing of Gram-negative bacteria in bloodstream infections

G Descours, L Desmurs, TLT Hoang… - European Journal of …, 2018 - Springer
Identification and antimicrobial susceptibility testing (AST) are critical steps in the
management of bloodstream infections. Our objective was to evaluate the performance of the …

Minimum inhibitory concentration (MIC) distribution among wild-type strains of Legionella pneumophila identifies a subpopulation with reduced susceptibility to …

M Vandewalle-Capo, C Massip, G Descours… - International journal of …, 2017 - Elsevier
Legionnaires' disease is a severe pneumonia mainly caused by Legionella pneumophila
that is treated by antibiotics. The purpose of this study was to describe the susceptibility of …

Macrolide resistance in Legionella pneumophila: the role of LpeAB efflux pump

C Massip, G Descours, C Ginevra… - Journal of …, 2017 - academic.oup.com
Objectives: A previous study on 12 in vitro-selected azithromycin-resistant Legionella
pneumophila lineages showed that ribosomal mutations were major macrolide resistance …

Ribosomal mutations conferring macrolide resistance in Legionella pneumophila

G Descours, C Ginevra, N Jacotin, F Forey… - Antimicrobial agents …, 2017 - Am Soc Microbiol
… C-to-T and -G transitions were responsible for higher MICs than the C-to-A transition, as …
, Ieven M, Ortqvist A, Schaberg T, Torres A, van der Heijden G, Read R, and Verheij TJ. 2011. …