Three inherited autosomal dominant conditions—BRCA-related hereditary breast and
ovarian cancer (HBOC), Lynch syndrome (LS) and familial hypercholesterolemia (FH)—have …

Auditors of a large terminology, such as SNOMED CT, face a daunting challenge. To aid them
in their efforts, it is essential to devise techniques that can automatically identify concepts …

Understanding the impact of rare variants is essential to understanding human health. We
analyze rare (MAF < 0.1%) variants against 4264 phenotypes in 49,960 exome-sequenced …

Genome-wide association studies have identified 240 independent loci associated with type
2 diabetes (T2D) risk, but this knowledge has not advanced precision medicine. In contrast, …

SARS-CoV-2 is responsible for the ongoing world-wide pandemic which has already taken
more than two million lives. Effective treatments are urgently needed. The enzymatic activity …

Background Air pollution has been linked to increased susceptibility to SARS-CoV-2. Thus,
it has been suggested that wildfire smoke events may exacerbate the COVID-19 pandemic. …

Recent data suggests that culture isolations and susceptibility profiles are overlooked,
misinterpreted and are not a major determinant in the process of selecting anti-bacterial therapy. …

We have developed several prototype applications which integrate clinical systems with on-line
information resources by using patient data to drive queries in response to user …

Background Health risks due to particulate matter (PM) from wildfires may differ from risk due
to PM from other sources. In places frequently subjected to wildfire smoke, such as Reno, …

… -g dose of fosfomycin trometamol for the treatment of uncomplicated lower urinary tract infections
in women compared with a 5-day regimen of cephalexin at 0.5 g … a single 3-g dose is as …