Although rodent glioblastoma (GBM) models have been used for over 30 years, the extent
to which they recapitulate the characteristics encountered in human GBMs remains …

On September 14–15, 2015, a meeting of clinicians and investigators in the fields of veterinary
and human neuro-oncology, clinical trials, neuropathology, and drug development was …

Postoperative analgesia provided by transdermal fentanyl was compared with that provided
by epidural morphine in dogs undergoing major orthopedic surgery. Dogs randomly were …

Neurofibromatosis Type 1 (NF1) is a genetic disease caused by mutations in Neurofibromin
1 (NF1). NF1 patients present with a variety of clinical manifestations and are predisposed to …

Dogs with naturally occurring cancer represent an important large animal model for drug
development and testing novel immunotherapies. However, poorly defined immunophenotypes …

… effects of HLA-G expressed on gliomas. Wiendl et al. first reported that HLA-G expression
by … Subsequent studies confirmed and extended this work to show that HLA-G is frequently …

Purpose: Advances in immunotherapy have revolutionized care for some patients with cancer.
However, current checkpoint inhibitors are associated with significant toxicity and yield …

This study was designed to determine whether dietary fish oil affects the expression and
activity of matrix metalloproteinases (MMP), tissue inhibitors of MMP-2 (TIMP-2) and urokinase …

… the defect and 10 g (… g of the cranial tibialis muscle and 2.5 to 4 g of gastrocnemius muscle
were removed. Excised tissue was placed in a tarred dish on a digital scale until a total of 10 g …

Recent advances in immunotherapy have included inhibition of immune checkpoint
proteins in the tumor microenvironment and tumor lysate-based vaccination strategies. We …