User profiles for G. Formenti

Giulio Formenti

The Rockefeller University
Verified email at rockefeller.edu
Cited by 5267

[HTML][HTML] The era of reference genomes in conservation genomics

G Formenti, K Theissinger, C Fernandes, I Bista… - Trends in ecology & …, 2022 - cell.com
Progress in genome sequencing now enables the large-scale generation of reference genomes.
Various international initiatives aim to generate reference genomes representing global …

[HTML][HTML] How genomics can help biodiversity conservation

K Theissinger, C Fernandes, G Formenti, I Bista… - Trends in genetics, 2023 - cell.com
The availability of public genomic resources can greatly assist biodiversity assessment,
conservation, and restoration efforts by providing evidence for scientifically informed …

[HTML][HTML] Long walk to genomics: History and current approaches to genome sequencing and assembly

…, GR Gallo, L Gianfranceschi, G Formenti - Computational and …, 2020 - Elsevier
Genomes represent the starting point of genetic studies. Since the discovery of DNA structure,
scientists have devoted great efforts to determine their sequence in an exact way. In this …

The complete sequence of a human genome

…, R Durbin, T Dvorkina, IT Fiddes, G Formenti… - Science, 2022 - science.org
Since its initial release in 2000, the human reference genome has covered only the
euchromatic fraction of the genome, leaving important heterochromatic regions unfinished. …

[HTML][HTML] Towards complete and error-free genome assemblies of all vertebrate species

A Rhie, SA McCarthy, O Fedrigo, J Damas, G Formenti… - Nature, 2021 - nature.com
… h, Correlation between estimated chromosome sizes (in Mb) based on karyotype images
in g and assembled scaffolds in Supplementary Table 4 (bCalAna1) on a log–log scale. v1.0, …

[HTML][HTML] MitoHiFi: a python pipeline for mitochondrial genome assembly from PacBio high fidelity reads

…, JGRN Ferreira, K Krasheninnikova, G Formenti… - BMC …, 2023 - Springer
Background PacBio high fidelity (HiFi) sequencing reads are both long (15–20 kb) and
highly accurate (> Q20). Because of these properties, they have revolutionised genome …

[HTML][HTML] A draft human pangenome reference

…, S Fairley, O Fedrigo, AL Felsenfeld, G Formenti… - Nature, 2023 - nature.com
g, Flagger read-based assembly evaluation pipeline. Coverage is calculated across the
genome … g, Dotplot illustrating SPDYE2–SPDYE2B haplotype resolved gains within a tandem …

The earth BioGenome project 2020: Starting the clock

…, O Fedrigo, P Flicek, G Formenti… - Proceedings of the …, 2022 - National Acad Sciences
November 2020 marked 2 y since the launch of the Earth BioGenome Project (EBP), which
aims to sequence all known eukaryotic species in a 10-y timeframe. Since then, significant …

The complete sequence of a human Y chromosome

…, NC Chen, CS Chin, M Diekhans, P Flicek, G Formenti… - Nature, 2023 - nature.com
The human Y chromosome has been notoriously difficult to sequence and assemble
because of its complex repeat structure that includes long palindromes, tandem repeats and …

[HTML][HTML] Semi-automated assembly of high-quality diploid human reference genomes

ED Jarvis, G Formenti, A Rhie, A Guarracino, C Yang… - Nature, 2022 - nature.com
The current human reference genome, GRCh38, represents over 20 years of effort to generate
a high-quality assembly, which has benefitted society 1 , 2 . However, it still has many …