The advent of high throughput next generation sequencing (NGS) has accelerated the pace
of discovery of disease-associated genetic variants and genomewide profiling of expressed …

Gene regulatory networks (GRNs) guiding differentiation of cell types and cell assemblies in
the nervous system are poorly understood because of inherent complexities and …

COVID-19, caused by the novel SARS-CoV-2 virus, started in China in late 2019, and soon
became a global pandemic. With the help of thousands of viral genome sequences that have …

SARS-CoV-2 is a betacoronavirus responsible for COVID-19, a pandemic with global
impact that first emerged in late 2019. Since then, the viral genome has shown considerable …

MicroRNAs (miRNA) are small endogenous RNA molecules, which regulate target gene
expression at post-transcriptional level. Besides, miRNA activity can be controlled by a newly …

Alzheimer's disease (AD) is one of the most severe neurodegenerative diseases observed
in the elderly population. Although the hallmarks of AD have been identified, the methods for …

Background The last decade witnessed a number of genome-wide studies on human pre-implantation,
which mostly focused on genes and provided only limited information on repeats, …

Keratins (KRTs) are the intermediate filament-forming proteins of epithelial cells, classified,
according to their physicochemical properties, into “soft” and “hard” keratins. They have a key …

Background TNF-related apoptosis-inducing ligand (TRAIL) is a member of the TNF
superfamily that can either induce cell death or activate survival pathways after binding to death …

Introduction Recent studies highlight the crucial regulatory roles of transposable elements (TEs)
on proximal gene expression in distinct biological contexts such as disease and …