User profiles for G. Khare

Garima Khare

University of Delhi south campus
Verified email at south.du.ac.in
Cited by 839

Mechanism of action of 1-β-D-ribofuranosyl-1, 2, 4-triazole-3-carboxamide (Virazole), a new broad-spectrum antiviral agent

DG Streeter, JT Witkowski, GP Khare… - Proceedings of the …, 1973 - National Acad Sciences
The antiviral activity of the synthetic nucleoside, Virazole (1-β-D-ribofuranosyl-1,2,4-triazole-3-carboxamide),
against measles virus in Vero cell cultures was substantially reversed by …

[HTML][HTML] The disease progression of Mecp2 mutant mice is affected by the level of BDNF expression

Q Chang, G Khare, V Dani, S Nelson, R Jaenisch - Neuron, 2006 - cell.com
Mutations in the MECP2 gene cause Rett syndrome (RTT). Bdnf is a MeCP2 target gene;
however, its role in RTT pathogenesis is unknown. We examined Bdnf conditional mutant mice …

Outcomes and complications of fractures of distal radius (AO type B and C): volar plating versus nonoperative treatment

H Sharma, GN Khare, S Singh, AG Ramaswamy… - Journal of Orthopaedic …, 2014 - Springer
Objectives Management of AO type B and C fractures of the distal radius is controversial.
This study compares outcomes and complications of AO type B and C fractures of the distal …

In Vitro Effect of 1-β-d-Ribofuranosyl-1,2,4-Triazole-3-Carboxamide (Virazole, ICN 1229) on Deoxyribonucleic Acid and Ribonucleic Acid Viruses

JH Huffman, RW Sidwell, GP Khare… - Antimicrobial agents …, 1973 - Am Soc Microbiol
Virazole (1-β-d-ribofuranosyl-1,2,4-triazole-3-carboxamide) is a highly soluble new
synthetic nucleoside having significant, reproducible activity against a broad spectrum of …

Synthesis of novel 1, 2, 3-triazole derivatives of isoniazid and their in vitro and in vivo antimycobacterial activity evaluation

D Kumar, G Khare, S Kidwai, AK Tyagi, R Singh… - European journal of …, 2014 - Elsevier
We report herein the synthesis and antimycobacterial activity of 1,2,3-triazole derivatives of
isoniazid. Most of the compounds exhibited potent activity against Mycobacterium …

Synthesis and antiviral activity of 1, 2, 4-triazole-3-thiocarboxamide and 1, 2, 4-triazole-3-carboxamidine ribonucleosides

JT Witkowski, RK Robins, GP Khare… - Journal of Medicinal …, 1973 - ACS Publications
… In this study,14-16-g Swiss mice were exposed to an aerosol14 of the virus in a concentration
sufficient to kill 75% of the placebo-treated control animals. Intraperitoneal treatment, with …

Clerodendrum serratum: A clinical approach

MK Singh, G Khare, SK Iyer, G Sharwan… - Journal of Applied …, 2012 - japsonline.com
Clerodendrum serratum Linn.(Family: Verbenaceae) is very widely distributed in tropical
and subtropical regions of the world. Ethno-medicinal importance of the plant has been …

[HTML][HTML] Edaravone guards dopamine neurons in a rotenone model for Parkinson's disease

N Xiong, J Xiong, G Khare, C Chen, J Huang, Y Zhao… - PLoS …, 2011 - journals.plos.org
3-methyl-1-phenyl-2-pyrazolin-5-one (edaravone), an effective free radical scavenger,
provides neuroprotection in stroke models and patients. In this study, we investigated its …

[HTML][HTML] Ferritin Structure from Mycobacterium tuberculosis: Comparative Study with Homologues Identifies Extended C-Terminus Involved in Ferroxidase Activity

G Khare, V Gupta, P Nangpal, RK Gupta, NK Sauter… - PloS one, 2011 - journals.plos.org
Ferritins are recognized as key players in the iron storage and detoxification processes. Iron
acquisition in the case of pathogenic bacteria has long been established as an important …

Common ophthalmic emergencies

GD Khare, RC Andrew Symons… - International journal of …, 2008 - Wiley Online Library
Ophthalmic emergencies are immediate threats to the visual system that can lead to
permanent loss of visual function if left untreated. These emergencies should be detected by …