Celecoxib potentiates antibiotic uptake by altering membrane potential and permeability in Staphylococcus aureus

GYN Varma, G Kummari, P Paik… - Journal of Antimicrobial …, 2019 - academic.oup.com
Background We have shown previously that celecoxib enhances the antibacterial effect of
antibiotics and has sensitized drug-resistant bacteria to antibiotics at low concentrations using …

Performance analysis of machine learning algorithms for gender classification

LN Pondhu, G Kummari - 2018 Second International …, 2018 - ieeexplore.ieee.org
We have various machine algorithms for gender classification but choosing best one is
important task. For selecting best algorithm we conducted experimental study on machine …

Protein kinase A mediates novel serine-584 phosphorylation of HDAC4

SK Doddi, G Kummari, J MV… - Biochemistry and Cell …, 2019 - cdnsciencepub.com
Given the well-established diversified signaling pathways for histone deacetylase 4 (HDAC4)
and the regulation of HDAC4 by several post-translational modifications (PTMs), including …

Abstract A024: Preclinical profile of novel and potent small molecule inhibitors of KIF18A inhibitors in chromosomally unstable solid tumor lines

…, N Karche, G Gudade, V Sankeshi, G Kummari… - Molecular Cancer …, 2023 - AACR
Accurate alignment of chromosomes at the equator region and equal chromosome separation
during cell division is essential for maintenance of genome integrity. KIF18A belongs to …

Preclinical profile of novel and potent small molecule inhibitors of PARG

S Patra, M Pothuganti, G Kummari, V Sankeshi… - Cancer Research, 2024 - AACR
Poly(ADP-ribose) glycohydrolase (PARG) is primary enzyme involved in the dePARylation
process of DNA repair, specifically in the single strand break repair (SSBRs). PARG is a …

[HTML][HTML] Association of CYBA gene (-930 A/G and 242 C/T) polymorphisms with oxidative stress in breast cancer: a case-control study

…, K Kupsal, N Shyamala, S Gantala, R Kummari… - PeerJ, 2018 - peerj.com
… Our insilco analysis on transcription-factor binding sites with respect to -930 A/G polymorphic
variants revealed that the substitution of A by G results in the loss of repressor C/EBPbeta …

HDAC6 promotes PMA-induced megakaryocyte differentiation of K562 cells by regulating ROS levels via NOX4 and repressing Glycophorin A

G Kummari, RK Gutti, AM Kalle - bioRxiv, 2019 - biorxiv.org
… at 10000 g for 3 min. The pelleted nuclei were washed with cytosolic extraction buffer and
spun at 16000 g for 5 min. The … The nuclear extract was collected at 16000 g for 30 min at 4C. …

Abstract A099: Best in class, potent, SOS1 inhibitors demonstrate single agent activity in preclinical models of KRAS driven tumors

B Lakhavath, M Pothuganti, G Kummari… - Molecular Cancer …, 2023 - AACR
KRAS is an oncogene implicated in a wide variety of tumors (~21% of solid tumors harbor
KRAS mutations). Interaction of KRAS with its predominant Guanine Exchange Factor (GEF), …

Design and synthesis of Pd decorated rGO-MoSe2 2D hybrid network as high performance electrocatalyst toward methanol electrooxidation

SK Venishetty, S Kummari, S Karingula, S Moru… - International Journal of …, 2023 - Elsevier
… In brief, 2 g of graphite powder was added to 70 mL of ice-cold conc. H 2 SO 4 in 500 mL …
then add 1.5 g NaNO 3 followed by stirring about 10 min for uniform mixing. Then, 6 g KMnO 4 …

[HTML][HTML] Root and Leaf Anatomy, Ion Accumulation, and Transcriptome Pattern under Salt Stress Conditions in Contrasting Genotypes of Sorghum bicolor

AR Karumanchi, P Sivan, D Kummari, G Rajasheker… - Plants, 2023 - mdpi.com
Roots from salt-susceptible ICSR-56 (SS) sorghum plants display metaxylem elements with
thin cell walls and large diameter. On the other hand, roots with thick, lignified cell walls in …