Clinical trials with antiangiogenic agents have not been able to validate plasma or serum
levels of angiogenesis regulators as reliable markers of cancer presence or therapeutic …

… between the PPI entropy and Gibbs free energy for cancer cells, namely G = 7873 − 932S.
Note that in order to relate G and S, we used the absolute value of the Gibbs free energy. This …

The administration of chemotherapy at reduced doses given at regular, frequent time
intervals, termed ‘metronomic’ chemotherapy, presents an alternative to standard maximal …

… Formally, an automorphism g of a graph G, has the property that for two vertices u, and v, u
g is adjacent to v g if and only if, v is adjacent to u (ie an edge exists between vertices u and v)…

With the recent addition of anti-angiogenic agents to cancer treatment, the angiogenesis
regulators in platelets are gaining importance. Platelet factor 4 (PF-4/CXCL4) and Connective …

Platelets, as initial responders to vascular injury, play a very important role in the initial
stages of the haemostatic process. While the role of platelets in coagulation has been well …

… and α2β1, are not coupled to G-proteins (27). To elucidate whether the differential effect of
pH on alpha granule release was related to a specific G-protein-related signalling pathway, …

Both normal wound healing and tumor angiogenesis are mitigated by the sequential, carefully
orchestrated release of growth stimulators and inhibitors. These regulators are released …

Purpose The role of angiogenesis in the transformation of peripheral neurofibroma (PNF) to
malignant peripheral nerve sheath tumor (MPNST) in neurofibromatosis type 1 (NF1) …

Research has exposed cancer to be a heterogeneous disease with a high degree of inter-tumoral
and intra-tumoral variability. Individual tumors have unique profiles, and these …