Aging leads to increased cellular senescence and is associated with decreased potency of
tissue‐specific stem/progenitor cells. Here, we have done an extensive analysis of cardiac …

Multipotent adult resident cardiac stem cells (CSCs) were first identified by the expression of
c-kit, the stem cell factor receptor. However, in the adult myocardium c-kit alone cannot …

The coronavirus pandemic has reportedly infected over 31.5 million individuals and caused
over 970,000 deaths worldwide (as of 22nd Sept 2020). This novel coronavirus, officially …

Senescent cell accumulation has been observed in age-associated diseases including
cardiovascular diseases. Senescent cells lack proliferative capacity and secrete senescence-…

… A mouse hematopoietic system genetically modified to lack the transcription factors FoxO1,
FoxO3, and FoxO4, which are downstream effectors of the insulin and insulin-like growth …

… Ellison-Hughes and Daniele Torella share the seniorship for the study. … Weisz, Bernardo
Nadal-Ginard, Georgina M Ellison-Hughes, Daniele Torella, Atrial myxomas arise from …

Heart failure is the number one killer worldwide with ~50% of patients dying within 5 years of
prognosis. The discovery of stem cells, which are capable of repairing the damaged portion …

The global pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that
causes coronavirus disease 2019 (COVID-19) has led to 47 m infected cases and 1. 2 m (…

The increasing life expectancy of the world population has become an economic and global
public health problem. Increased life expectancy tracks with a higher incidence of multiple …

An overdose of Isoproterenol (ISO) causes acute cardiomyocyte (CM) dropout and activates
the resident cardiac c-kit pos stem/progenitor cells (CSCs) generating a burst of new CM …