User profiles for G. Rajadinakaran

Gopinath Rajadinakaran

The Jackson Laboratory
Verified email at jax.org
Cited by 261

[HTML][HTML] Sensory hair cell death and regeneration in fishes

JD Monroe, G Rajadinakaran, ME Smith - Frontiers in cellular …, 2015 - frontiersin.org
Sensory hair cells are specialized mechanotransductive receptors required for hearing and
vestibular function. Loss of hair cells in humans and other mammals is permanent and …

[HTML][HTML] Determining exon connectivity in complex mRNAs by nanopore sequencing

MT Bolisetty, G Rajadinakaran, BR Graveley - Genome biology, 2015 - Springer
Short-read high-throughput RNA sequencing, though powerful, is limited in its ability to
directly measure exon connectivity in mRNAs that contain multiple alternative exons located …

[HTML][HTML] The transcriptomics to proteomics of hair cell regeneration: looking for a hair cell in a haystack

ME Smith, G Rajadinakaran - Microarrays, 2013 - mdpi.com
Mature mammals exhibit very limited capacity for regeneration of auditory hair cells, while all
non-mammalian vertebrates examined can regenerate them. In an effort to find therapeutic …

Oxford Nanopore Technology: A Promising Long-Read Sequencing Platform To Study Exon Connectivity and Characterize Isoforms of Complex Genes

G Rajadinakaran - 2018 - digitalcommons.lib.uconn.edu
The central dogma states that the genetic information contained in DNA flows to RNA through
the process of transcription which, in turn, can result in protein synthesis through translation…

[HTML][HTML] Regulation of cell proliferation and apoptosis by growth hormone during zebrafish auditory hair cell regeneration

G Rajadinakaran, H Sun, C Rinehart, E Rouchka… - BMC …, 2012 - Springer
Background In order to develop treatments or preventive measures for auditory hair cell loss,
an understanding of both the process of auditory hair cell regeneration and factors that …

Next Generation Sequencing Reveals Gene Expression Patterns in the Zebrafish Inner Ear Following Growth Hormone Injection

G Rajadinakaran - 2012 - digitalcommons.wku.edu
Loss of hair cells due to acoustic trauma results in the loss of hearing. In humans, unlike
other vertebrates, the mechanism of hair cell regeneration is not possible. The molecular …

The Transcriptomics to Proteomics of Hair Cell Regeneration: Looking for a Hair Cell in a Haystack

G Rajadinakaran - 2013 - digitalcommons.lib.uconn.edu
… Forge A, Li L, Corwin JT, Nevill G. Ultrastructural evidence for hair cell regeneration in the
… Forge A, Nevill G. Hair cell recovery in the vestibular sensory epithelia of mature guinea pigs…

Automation of combustion monitoring in boilers using discriminant radial basis network

…, K Senthil Kumar, CR Raja Dinakaran - … Journal of Artificial …, 2013 - inderscienceonline.com
This research work aims at monitoring and control of the combustion quality in a power
station, coal fired boiler using a combination of Fisher’s linear discriminant (FLD) analysis and …

The curcuminoid, EF-24, reduces cisplatin-mediated reactive oxygen species in zebrafish inner ear auditory and vestibular tissues

JD Monroe, MH Millay, BG Patty, ME Smith - Journal of Clinical …, 2018 - Elsevier
Cisplatin is a widely used chemotherapy drug that can damage auditory and vestibular tissue
and cause hearing and balance loss through the intracellular release of reactive oxygen …

[CITATION][C] Sensory hair cell death and regeneration in fishes. Front Cell Neurosci 9: 131

JD Monroe, G Rajadinakaran, ME Smith - 2015