Publisher Summary The traveling salesman problem, TSP for short, has model character in
many branches of mathematics, computer science, and operations research. Heuristics, …

… The weight of each edge e We represent (G, 5) by a data structure that is used commonly
forsparse graphs. The nodes of V are indexed with the integers {1,..., ]V }, the edges of F are …

… results of our current computational study will be reported in Padberg and Rinaldi [11]. To
calculate the optimal tour displayed in Figure 1, we developed a software system written …

BRCA1 and BRCA2 germline mutations contribute to a significant number of familial and
hereditary breast and/or ovarian cancers. The proportion of high-risk families with breast and/or …

Schistosomiasis, a major neglected tropical disease, affects more than 250 million people
worldwide. Treatment of schistosomiasis has relied on the anthelmintic drug praziquantel (PZQ…

… The paths are enumerated recursively; at each step we consider all the ways of enlarging a
path in G(x) by adding two nodes. The number of possibilities is not too large because G(x) is …

In 1958, Ralph E. Gomory transformed the field of integer programming when he published
a short paper that described his cutting-plane algorithm for pure integer programs and …

Schistosomiasis is a neglected tropical disease caused by blood flukes (genus Schistosoma;
schistosomes) and affecting 200 million people worldwide 1 . No vaccines are available, …

The VIRTIS (Visible, Infrared and Thermal Imaging Spectrometer) instrument on board the
Rosetta spacecraft has provided evidence of carbon-bearing compounds on the nucleus of …

… Lastly, we identify a signature with a defined C>T peak at GCG, SBS97, most closely
resembling SBS15; however, it can be distinguished from SBS15 by strong T>C at …