Lipid metabolism in insect disease vectors
KC Gondim, GC Atella, EG Pontes… - Insect biochemistry and …, 2018 - Elsevier
More than a third of the world population is at constant risk of contracting some insect-transmitted
disease, such as Dengue fever, Zika virus disease, malaria, Chagas' disease, African …
disease, such as Dengue fever, Zika virus disease, malaria, Chagas' disease, African …
[HTML][HTML] Oogenesis and egg development in triatomines: a biochemical approach
GC Atella, KC Gondim, EA Machado… - Anais da Academia …, 2005 - SciELO Brasil
In triatomines, as well as in other insects, accumulation of yolk is a process in which an extra-ovarian
tissue, the fat body, produces yolk proteins that are packed in the egg. The main …
tissue, the fat body, produces yolk proteins that are packed in the egg. The main …
Genome of Rhodnius prolixus, an insect vector of Chagas disease, reveals unique adaptations to hematophagy and parasite infection
… A1), with a measured GC content of 27.1% that was slightly lower than that of another
hemipteran, the pea aphid, Acyrthosiphon pisum (29.2%), although comparable GC content was …
hemipteran, the pea aphid, Acyrthosiphon pisum (29.2%), although comparable GC content was …
Lipid droplet formation in leprosy: Toll-like receptor-regulated organelles involved in eicosanoid formation and Mycobacterium leprae pathogenesis
…, VGC Oliveira, EN Sarno, GC Atella… - Journal of leukocyte …, 2010 - academic.oup.com
Lipid droplets induced by Mycobacterium leprae in macrophages are Toll-like receptor-regulated
organelles involved in eicosanoid formation and leprosy pathogenesis. A hallmark of …
organelles involved in eicosanoid formation and leprosy pathogenesis. A hallmark of …
[HTML][HTML] An Insight into the Transcriptome of the Digestive Tract of the Bloodsucking Bug, Rhodnius prolixus
…, KC Gondim, MAC Silva-Neto, GC Atella… - PLOS neglected …, 2014 - journals.plos.org
The bloodsucking hemipteran Rhodnius prolixus is a vector of Chagas' disease, which affects
7–8 million people today in Latin America. In contrast to other hematophagous insects, the …
7–8 million people today in Latin America. In contrast to other hematophagous insects, the …
Mycobacterium leprae intracellular survival relies on cholesterol accumulation in infected macrophages: a potential target for new drugs for leprosy treatment
…, EN Sarno, PT Bozza, GC Atella… - Cellular …, 2014 - Wiley Online Library
We recently showed that M ycobacterium leprae ( ML ) is able to induce lipid droplet formation
in infected macrophages. We herein confirm that cholesterol ( Cho ) is one of the host lipid …
in infected macrophages. We herein confirm that cholesterol ( Cho ) is one of the host lipid …
[HTML][HTML] Proliferation and Differentiation of Trypanosoma cruzi inside Its Vector Have a New Trigger: Redox Status
…, KCC Sabino, MGP Coelho, A Rossini, GC Atella… - PloS one, 2015 - journals.plos.org
Trypanosoma cruzi proliferate and differentiate inside different compartments of triatomines
gut that is the first environment encountered by T. cruzi. Due to its complex life cycle, the …
gut that is the first environment encountered by T. cruzi. Due to its complex life cycle, the …
[HTML][HTML] Lysophosphatidylcholine triggers TLR2-and TLR4-mediated signaling pathways but counteracts LPS-induced NO synthesis in peritoneal macrophages by …
Background Lysophosphatidylcholine (LPC) is the main phospholipid component of
oxidized low-density lipoprotein (oxLDL) and is usually noted as a marker of several human …
oxidized low-density lipoprotein (oxLDL) and is usually noted as a marker of several human …
Leishmanicidal effects of piperine, its derivatives, and analogues on Leishmania amazonensis
Leishmaniasis is a tropical disease caused by protozoan parasites of the genus Leishmania
which affects 12million people worldwide. The discovery of drugs for the treatment of …
which affects 12million people worldwide. The discovery of drugs for the treatment of …
[HTML][HTML] Antioxidant role of Rhodnius prolixus heme-binding protein: protection against heme-induced lipid peroxidation
M Dansa-Petretski, JMC Ribeiro, GC Atella… - Journal of Biological …, 1995 - ASBMB
Heme in aqueous solutions actively promotes free radical reactions leading to degradation
of biological molecules. The blood-sucking insect Rhodnius prolixus has a heme-binding …
of biological molecules. The blood-sucking insect Rhodnius prolixus has a heme-binding …