… Beecham receives support from the National Institutes for Health: AG062695 (MPI) 2019-…
Beecham also receives support through the BrightFocus foundation: A2018425S (co-I) 2018…

Eleven susceptibility loci for late-onset Alzheimer's disease (LOAD) were identified by previous
studies; however, a large portion of the genetic risk for this disease remains unexplained. …

The Alzheimer Disease Genetics Consortium (ADGC) performed a genome-wide association
study of late-onset Alzheimer disease using a three-stage design consisting of a discovery …

Risk for late-onset Alzheimer’s disease (LOAD), the most prevalent dementia, is partially
driven by genetics. To identify LOAD risk loci, we performed a large genome-wide association …

We identified rare coding variants associated with Alzheimer's disease in a three-stage case–control
study of 85,133 subjects. In stage 1, we genotyped 34,174 samples using a whole-…

Parkinson disease (PD) is a chronic neurodegenerative disorder with a cumulative prevalence
of greater than one per thousand. To date three independent genome‐wide association …

Objectives: To determine whether genotypes at CLU, PICALM, and CR1 confer risk for
Alzheimer disease (AD) and whether risk for AD associated with these genes is influenced by …

INTRODUCTION Across human societies and in both sexes, some 2 to 10% of individuals
report engaging in sex with same-sex partners, either exclusively or in addition to sex with …

Alzheimer's disease (AD) and related dementias are a major public health challenge and
present a therapeutic imperative for which we need additional insight into molecular …

Objective: Genome‐wide association (GWAS) methods have identified genes contributing
to Parkinson's disease (PD); we sought to identify additional genes associated with PD …