User profiles for Gabriel M. Gihana

Gabriel Muhire Gihana

UT Southwestern Medical Center
Verified email at utsouthwestern.edu
Cited by 66

Blebs promote cell survival by assembling oncogenic signalling hubs

…, BJ Chang, VS Murali, GM Gihana… - Nature, 2023 - nature.com
Most human cells require anchorage for survival. Cell–substrate adhesion activates diverse
signalling pathways, without which cells undergo anoikis—a form of programmed cell death …

Increasing the field-of-view in oblique plane microscopy via optical tiling

…, BA Nanes, I Terrazas, GM Gihana… - Biomedical Optics …, 2022 - opg.optica.org
Fast volumetric imaging of large fluorescent samples with high-resolution is required for
many biological applications. Oblique plane microscopy (OPM) provides high spatiotemporal …

The mitotic exit network regulates the spatiotemporal activity of Cdc42 to maintain cell size

GM Gihana, AA Cross-Najafi, S Lacefield - Journal of Cell Biology, 2020 - rupress.org
During G1 in budding yeast, the Cdc42 GTPase establishes a polar front, along which actin
is recruited to direct secretion for bud formation. Cdc42 localizes at the bud cortex and then …

[HTML][HTML] Surface-guided computing to analyze subcellular morphology and membrane-associated signals in 3D

…, A Weems, GM Gihana, B Chen, BJ Chang, M Driscoll… - ArXiv, 2023 - ncbi.nlm.nih.gov
Signal transduction and cell function are governed by the spatiotemporal organization of
membrane-associated molecules. Despite significant advances in visualizing molecular …

Prolonged cyclin-dependent kinase inhibition results in septin perturbations during return to growth and mitosis

GM Gihana, TR Musser, O Thompson… - Journal of Cell …, 2018 - rupress.org
We investigated how Saccharomyces cerevisiae coordinate polarization, budding, and anaphase
during a unique developmental program called return to growth (RTG) in which cells in …

[HTML][HTML] Gabriel Muhire Gihana: A candle loses nothing by lighting other candles

MA O'Donnell - The Journal of Cell Biology, 2019 - ncbi.nlm.nih.gov
Gihana investigates how cells coordinate their shape … , Gabriel Muhire Gihana scored
among the top students on national tests that determine university placements. As a result, Gihana

Comparison of 200 mg/m2 melphalan and 8 Gy total body irradiation plus 140 mg/m2 melphalan as conditioning regimens for peripheral blood stem cell …

…, T Facon, M Attal, C Hulin, M Michallet… - Blood, The Journal …, 2002 - ashpublications.org
… We conclude that 200 mg/m 2 melphalan is a less toxic and at least as effective conditioning
regimen when compared with 8 Gy total body irradiation with 140 mg/m 2 melphalan. This …

Human melanoma metastasis in NSG mice correlates with clinical outcome in patients

E Quintana, E Piskounova, M Shackleton… - Science translational …, 2012 - science.org
Studies of human cancer metastasis have been limited by a lack of experimental assays in
which cancer cells from patients metastasize in vivo in a way that correlates with clinical …

Synergistic Effect of Human Chorionic Gonadotropin and Granulocyte Colony Stimulating Factor in the Mobilization of HSPCs Improves Overall Survival After PBSCT …

CA Cismaru, C Tomuleasa, A Jurj, S Chira… - Stem Cell Reviews and …, 2024 - Springer
Strategies to improve hematopoietic stem and progenitor cell (HSPC) mobilization from the
bone marrow can have a pivotal role in addressing iatrogenic bone-marrow insufficiency …