Most biological processes are performed by multiprotein complexes. Traditionally described
as static entities, evidence is now emerging that their components can be highly dynamic, …

Objectives Decades of empirical research demonstrate that crime is concentrated at a range
of spatial scales, including street segments. Further, the degree of clustering at particular …

Tumour‐associated microglia/macrophages ( TAM ) are the most numerous non‐neoplastic
populations in the tumour microenvironment in glioblastoma multiforme ( GBM ), the most …

Many physical and sociological processes are represented as discrete events in time and
space. These spatio-temporal point processes are often sparse, meaning that they cannot be …

Deregulation of chromatin modifiers plays an essential role in the pathogenesis of
medulloblastoma, the most common paediatric malignant brain tumour. Here, we identify a BMI1-…

Epigenetic mechanisms which play an essential role in normal developmental processes,
such as self-renewal and fate specification of neural stem cells (NSC) are also responsible for …

We describe molecular convergence between BMI1 and CHD7 in the initiation of medulloblastoma.
Identified in a functional genomic screen in mouse models, a BMI1 High ;CHD7 Low …

Objective In the trials, a substantial proportion of newborns who underwent therapeutic
hypothermia (TH) had an adverse outcome after hypoxic-ischaemic encephalopathy (HIE). …

The probability hypothesis density (PHD) filter from the theory of random finite sets is a well-known
method for multitarget tracking. We present the Gaussian mixture (GM) and improved …

The self-exciting point process (SEPP) is a model of the spread of crime in space and time,
incorporating background and triggering processes. It shows promising predictive …