Cellular senescence is known to play a role in age-related skin function deterioration which
potentially influences longevity. Here, a two-step phenotypic screening was performed to …

Cancers have a strong relationship with immune cells in their microenvironment, which
significantly influences tumor proliferation and progression. Thus, pharmacological strategies …

The skin is our largest organ and the outermost protective barrier. Its aging reflects both
intrinsic and extrinsic processes resulting from the constant insults it is exposed to. Aging in the …

Melanoma is one of the most aggressive tumors, and its lethality is associated with the ability
of malignant cells to migrate and invade surrounding tissues to colonize distant organs and …

O estudo das células mieloides (MDC) no microambiente tumoral (TME) é de extrema
importância na prática clínica oncológica. Essas células desempenham um papel crucial na …

Immunotherapies provide long-lasting responses across a wide range of cancers; however,
only a fraction of patients responds to them. Multiple reasons contribute to the failure, …

O Papilomavírus humano (HPV) é o agente da infecção viral mais comum que afeta o trato
reprodutor. É um vírus ubíquo e estima-se que mais de 50% dos indivíduos sexualmente …

INTRODUCTION AND OBJECTIVES: Ovarian cancer (OC) is the major cause of death related
to gynecological tumors, with high-grade serous ovarian cancer (HGSOC) being the most …

In this article, the authors found an unintended error in Fig. 6a that resulted in the duplication
of the no treatment image for the ex vivo skin of the 79yr female. These images were …

INTRODUCTION AND OBJECTIVES: Melanoma is a very aggressive and highly lethal
disease, being responsible for the majority of skin cancer-related deaths worldwide. The …