PURPOSE: Osteonecrosis of the jaw (ONJ) is a serious complication associated with
bisphosphonate therapy, but its epidemiology in the setting of oral bisphosphonate therapy is …

Since the late twentieth century,“citizen science” has become an increasingly fashionable
label for a growing number of participatory research activities. This paper situates the origins …

Background Psychological functioning is an important determinant of health outcomes in
chronic lung disease. To better define the role of anxiety in chronic obstructive pulmonary …

Background Although chronic obstructive pulmonary disease (COPD) is a common cause of
death and disability, little is known about the effects of socioeconomic status (SES) and race…

PURPOSE: Radiographic features in patients with bisphosphonate-related osteonecrosis of
the jaw (BRONJ) are well described, but less is known in bisphosphonate-exposed …

Targeted inhibition of oncogenic pathways can be highly effective in halting the rapid
growth of tumors but often leads to the emergence of slowly dividing persister cells, which …

Epigenetic regulation serves as the basis for stem cell differentiation into distinct cell types,
but it is unclear how global epigenetic changes are regulated during this process. Here, we …

METHODS The FLOW study is an ongoing prospective cohort study of adults recruited from
the membership of an integrated health care delivery system. 11, 12 All subjects carry a …

Chimeric antigen receptor (CAR) T cells targeting the CD19 antigen are effective in treating
adults and children with B-cell malignancies. Place-of-care manufacturing may improve …

Objective Helicobacter pylori causes life-long colonisation of the gastric mucosa, leading to
chronic inflammation with increased risk of gastric cancer. Research on the pathogenesis of …