User profiles for Gabriele Colozza
Gabriele ColozzaLise Meitner Scholar, Institute of Molecular Biotechnology (IMBA), Vienna Verified email at imba.oeaw.ac.at Cited by 523 |
Wnt/β‐catenin signaling: Structure, assembly and endocytosis of the signalosome
Wnt/β‐catenin signaling is an ancient pathway that regulates key aspects of embryonic
development, cell differentiation, proliferation, and adult stem cell homeostasis. Work from …
development, cell differentiation, proliferation, and adult stem cell homeostasis. Work from …
[PDF][PDF] GSK3 inhibits macropinocytosis and lysosomal activity through the Wnt destruction complex machinery
Canonical Wnt signaling is emerging as a major regulator of endocytosis. Here, we report
that Wnt-induced macropinocytosis is regulated through glycogen synthase kinase 3 (GSK3) …
that Wnt-induced macropinocytosis is regulated through glycogen synthase kinase 3 (GSK3) …
[PDF][PDF] Angiopoietin-like 4 is a Wnt signaling antagonist that promotes LRP6 turnover
Angiopoietin-like 4 (ANGPTL4) is a secreted signaling protein that is implicated in
cardiovascular disease, metabolic disorder, and cancer. Outside of its role in lipid metabolism, …
cardiovascular disease, metabolic disorder, and cancer. Outside of its role in lipid metabolism, …
Spemann organizer transcriptome induction by early beta-catenin, Wnt, Nodal, and Siamois signals in Xenopus laevis
The earliest event in Xenopus development is the dorsal accumulation of nuclear β-catenin
under the influence of cytoplasmic determinants displaced by fertilization. In this study, a …
under the influence of cytoplasmic determinants displaced by fertilization. In this study, a …
Bighead is a Wnt antagonist secreted by the Xenopus Spemann organizer that promotes Lrp6 endocytosis
The Xenopus laevis embryo has been subjected to almost saturating screens for molecules
specifically expressed in dorsal Spemann organizer tissue. In this study, we performed high-…
specifically expressed in dorsal Spemann organizer tissue. In this study, we performed high-…
[HTML][HTML] Genome-wide analysis of dorsal and ventral transcriptomes of the Xenopus laevis gastrula
RNA sequencing has allowed high-throughput screening of differential gene expression in
many tissues and organisms. Xenopus laevis is a classical embryological and cell-free …
many tissues and organisms. Xenopus laevis is a classical embryological and cell-free …
[HTML][HTML] Wnt-inducible Lrp6-APEX2 interacting proteins identify ESCRT machinery and Trk-fused gene as components of the Wnt signaling pathway
G Colozza, Y Jami-Alahmadi, A Dsouza… - Scientific reports, 2020 - nature.com
The canonical Wnt pathway serves as a hub connecting diverse cellular processes, including
β-catenin signaling, differentiation, growth, protein stability, macropinocytosis, and nutrient …
β-catenin signaling, differentiation, growth, protein stability, macropinocytosis, and nutrient …
Müller glial cell reactivation in Xenopus models of retinal degeneration
A striking aspect of tissue regeneration is its uneven distribution among different animal
classes, both in terms of modalities and efficiency. The retina does not escape the rule, …
classes, both in terms of modalities and efficiency. The retina does not escape the rule, …
Maternal syntabulin is required for dorsal axis formation and is a germ plasm component in Xenopus
G Colozza, EM De Robertis - Differentiation, 2014 - Elsevier
In amphibians and teleosts, early embryonic axial development is driven by maternally
deposited mRNAs and proteins, called dorsal determinants, which migrate to the presumptive …
deposited mRNAs and proteins, called dorsal determinants, which migrate to the presumptive …
Ub and Dub of RNF43/ZNRF3 in the WNT signalling pathway
The E3 ubiquitin ligases RING finger protein 43 (RNF43) and zinc and RING finger 3 (ZNRF3)
have received great attention for their critical role in regulating WNT signalling during …
have received great attention for their critical role in regulating WNT signalling during …