Concomitant tumor immunity describes immune responses in a host with a progressive tumor
that rejects the same tumor at a remote site. In this work, concomitant tumor immunity was …

Myeloid-derived suppressor cells (MDSC) are a heterogeneous population of cells that
accumulate during tumor formation, facilitate immune escape, and enable tumor progression. …

Cancer immunotherapies, including adoptive T cell transfer, can be ineffective because tumors
evolve to display antigen-loss-variant clones. Therapies that activate multiple branches of …

In vivo GITR ligation has previously been shown to augment T-cell-mediated anti-tumor
immunity, yet the underlying mechanisms of this activity, particularly its in vivo effects on CD4+ …

Expansion and recruitment of CD4 + Foxp3 + regulatory T (T reg) cells are mechanisms used
by growing tumors to evade immune elimination. In addition to expansion of effector T cells…

Background Intermittent treatment with sulfadoxine–pyrimethamine is widely recommended
for the prevention of malaria in pregnant women in Africa. However, with the spread of …

Immunization of mice with plasmids encoding xenogeneic orthologues of tumor differentiation
antigens can break immune ignorance and tolerance to self and induce protective tumor …

Immunoincompetence after allogeneic hematopoietic stem cell transplantation (HSCT) affects
in particular the T-cell lineage and is associated with an increased risk for infections, graft …

Beginning in the first trimester, fetally derived extravillous trophoblasts (EVTs) invade the
uterus and remodel its spiral arteries, transforming them into large, dilated blood vessels. …

While regulatory T (T reg ) cells are traditionally viewed as professional suppressors of antigen
presenting cells and effector T cells in both autoimmunity and cancer, recent findings of …