[HTML][HTML] Optical inhibition of larval zebrafish behaviour with anion channelrhodopsins

…, RK Cheng, J Ho, S Krishnan, F Mohammad… - BMC biology, 2017 - Springer
Background Optical silencing of activity provides a way to test the necessity of neurons in
behaviour. Two light-gated anion channels, GtACR1 and GtACR2, have recently been shown …

[HTML][HTML] Lineage plasticity enables low-ER luminal tumors to evolve and gain basal-like traits

GA Mohamed, S Mahmood, NB Ognjenovic… - Breast Cancer …, 2023 - Springer
Stratifying breast cancer into specific molecular or histologic subtypes aids in therapeutic
decision-making and predicting outcomes; however, these subtypes may not be as distinct as …

[PDF][PDF] Limiting self-renewal of the basal compartment by PKA activation induces differentiation and alters the evolution of mammary tumors

NB Ognjenovic, M Bagheri, GA Mohamed, K Xu… - Developmental cell, 2020 - cell.com
Differentiation therapy utilizes our understanding of the hierarchy of cellular systems to
pharmacologically induce a shift toward terminal commitment. While this approach has been a …

[HTML][HTML] Pharmacological Induction of mesenchymal-epithelial transition chemosensitizes breast cancer cells and prevents metastatic progression

M Bagheri, GA Mohamed, MAM Saleem… - bioRxiv, 2023 - ncbi.nlm.nih.gov
The epithelial-mesenchymal transition (EMT) is a developmental program co-opted by tumor
cells that aids the initiation of the metastatic cascade. Tumor cells that undergo EMT are …

Lineage plasticity enables low-ER luminal tumors to evolve and gain basal-like traits

GA Mohamed, S Mahmood, NB Ognjenovic, MK Lee… - bioRxiv, 2022 - biorxiv.org
Stratifying breast cancer into specific molecular or histological subtypes aids in therapeutic
decision-making and predicting outcomes, however, these subtypes may not be as distinct as …

[PDF][PDF] Optical inhibition of zebrafish behavior with anion channelrhodopsins

…, RK Cheng, J Ho, S Krishnan, F Mohammad… - scholar.archive.org
In behavioral analysis, optical electrical silencing provides a way to test neuronal necessity.
Two light-gated anion channels, GtACR1 and GtACR2, have recently been shown—in …

Eribulin alters the chromatin landscape to induce MET, attenuating metastatic progression sensitizing breast tumors to subsequent chemotherapy

M Bagheri, NB Ognjenovic, GA Mohamed, IS LaCroix… - Cancer Research, 2022 - AACR
Introduction: Two major hurdles faced in clinical cancer therapy are metastatic progression
that results in the majority of cancer deaths, and resistance to therapy that fuels tumor relapse…

Limiting Self-Renewal of the Basal Compartment Induces Differentiation and Alters Evolution of Mammary Tumors

…, K Xu, MS Brown, Y Chen, MA Mohamed Saleem… - bioRxiv, 2020 - biorxiv.org
Differentiation therapy is an approach that utilizes our understanding of the hierarchy of
cellular systems to pharmacologically induce a shift towards terminal commitment. While this …

UNDERSTANDING THE IMPLICATIONS OF LINEAGE PLASTICITY IN BREAST CANCER EVOLUTION AND CHEMOTHERAPY RESPONSE

GA Mohamed - 2023 - digitalcommons.dartmouth.edu
Intra-tumoral heterogeneity and the presence of a phenotypically diverse cell population
within a single tumor represents a major hurdle in the understanding of tumor progression and …

Optical inhibition of larval zebrafish behaviour with anion channelrhodopsins

…, RK Cheng, J Ho, S Krishnan, F Mohammad - 2017 - dr.ntu.edu.sg
Optical silencing of activity provides a way to test the necessity of neurons in behaviour. Two
light-gated anion channels, GtACR1 and GtACR2, have recently been shown to potently …