Expression of the type II voltage-dependent sodium channel gene is restricted to neurons
by a silencer element active in nonneuronal cells. We have cloned cDNA coding for a …

We have examined the regulation of somatostatin gene expression by cAMP in PC12 rat
pheochromocytoma cells transfected with the rat somatostatin gene. Forskolin at 10 microM …

Regulation of neuronal gene expression is critical to central nervous system development.
Here, we show that REST regulates the transitions from pluripotent to neural stem/progenitor …

MicroRNAs (miRNAs) are implicated in both tissue differentiation and maintenance of tissue
identity. In most cases, however, the mechanisms underlying their regulation are not known. …

Rett’s syndrome (RTT) is an X-chromosome-linked autism spectrum disorder caused by loss
of function of the transcription factor methyl-CpG-binding protein 2 (MeCP2) 1 . Although …

We describe the isolation and characterization of a cDNA encoding the α subunit of a new
voltage-sensitive sodium channel, μl, from rat skeletal muscle. The 1840 amino acid μl …

Voltage-dependent sodium channels are uniformly distributed along unmyelinated axons,
but are highly concentrated at nodes of Ranvier in myelinated axons. Here, we show that this …

Nervous system development relies on a complex signaling network to engineer the orderly
transitions that lead to the acquisition of a neural cell fate. Progression from the non-…

Sodium Channels synonyms for many of sodium channel isoforms. To eliminate confusion
resulting from the multiplicity of names, we propose a standardized nomenclature for Voltage-…

The CREB transcription factor regulates differentiation, survival, and synaptic plasticity. The
complement of CREB targets responsible for these responses has not been identified, …