[HTML][HTML] Emerging role of GLP-1 agonists in obesity: a comprehensive review of randomised controlled trials

…, L Păduraru, G Yahya, K Metwally… - International journal of …, 2023 - mdpi.com
Obesity is a chronic disease with high prevalence and associated comorbidities, making it a
growing global concern. These comorbidities include type 2 diabetes, hypertension, …

[HTML][HTML] Phytoestrogen β-Sitosterol Exhibits Potent In Vitro Antiviral Activity against Influenza A Viruses

…, AM Abbas, I Mostafa, IH Eissa, AM Metwaly, G Yahya… - Vaccines, 2023 - mdpi.com
Influenza is a contagious infection in humans that is caused frequently by low pathogenic
seasonal influenza viruses and occasionally by pathogenic avian influenza viruses (AIV) of H5, …

[HTML][HTML] Diabetes Mellitus Secondary to Endocrine Diseases: An Update of Diagnostic and Treatment Particularities

…, RM Nutas, AM Ujoc, G Yahya, K Metwally… - International Journal of …, 2023 - mdpi.com
Secondary diabetes mellitus is frequently ignored in specialized literature. In this narrative
review, the main endocrinopathies accompanied by increased glycemic values are identified, …

[HTML][HTML] The unusual architecture of RNA-dependent RNA polymerase (RdRp)'s catalytic chamber provides a potential strategy for combination therapy against …

K Metwally, NE Abo-Dya, MI Alahmdi, MZ Albalawi… - Molecules, 2023 - mdpi.com
The unusual and interesting architecture of the catalytic chamber of the SARS-CoV-2 RNA-dependent
RNA polymerase (RdRp) was recently explored using Cryogenic Electron …

Profiling the physiological pitfalls of anti‐hepatitis C direct‐acting agents in budding yeast

…, I Juraiby, K Metwally… - Microbial …, 2021 - Wiley Online Library
Sofosbuvir and Daclatasvir are among the direct‐acting antiviral (DAA) medications prescribed
for the treatment of chronic hepatitis C (CHC) virus infection as combination therapy with …

Regulatory and pathogenic mechanisms in response to iron deficiency and excess in fungi

…, K Krukiewicz, R Mosbah, K Metwally… - Microbial …, 2023 - Wiley Online Library
Iron is an essential element for all eukaryote organisms because of its redox properties,
which are important for many biological processes such as DNA synthesis, mitochondrial …

Revolutionizing Treatment Strategies for Autoimmune and Inflammatory Disorders: The Impact of Dipeptidyl-Peptidase 4 Inhibitors

…, MS Alturki, AH Al Khzem, K Metwally… - Journal of …, 2024 - Taylor & Francis
DPP4 (Dipeptidyl-peptidase 4) a versatile protease, emerges as a prominent player in soluble
and membrane-bound forms. Its heightened expression has been intimately linked to the …

[HTML][HTML] Molecular Understanding of ACE-2 and HLA-Conferred Differential Susceptibility to COVID-19: Host-Directed Insights Opening New Windows in COVID-19 …

…, H Tayyab, I Khan, M Khan, G Yahya… - Journal of Clinical …, 2023 - mdpi.com
The genetic variants of HLAs (human leukocyte antigens) play a crucial role in the virus–host
interaction and pathology of COVID-19. The genetic variants of HLAs not only influence T …

[HTML][HTML] Coronavirus disease (COVID-19) control between drug repurposing and vaccination: a comprehensive overview

…, A Abo Elmaaty, MA Tantawy, SA Antar, G Yahya… - Vaccines, 2021 - mdpi.com
Respiratory viruses represent a major public health concern, as they are highly mutated,
resulting in new strains emerging with high pathogenicity. Currently, the world is suffering from …

[PDF][PDF] Molecular retention mechanisms of the G1 cyclin/Cdk complex in budding yeast

GYAER Metwally - 2015 - core.ac.uk
I am completely indebted to Professors Martí Aldea and Carme Gallego, for their continuous
guidance and for many stimulating discussions. Their original insights and approach to …