User profiles for Galeb AbuAli

Galeb Abu-Ali

Janssen Pharmaceuticals
Verified email at its.jnj.com
Cited by 5483

[HTML][HTML] The healthy human microbiome

J Lloyd-Price, G Abu-Ali, C Huttenhower - Genome medicine, 2016 - Springer
Humans are virtually identical in their genetic makeup, yet the small differences in our DNA
give rise to tremendous phenotypic diversity across the human population. By contrast, the …

Sequencing and beyond: integrating molecular'omics' for microbial community profiling

…, T Hsu, A Sirota-Madi, A Shafquat, G Abu-Ali… - Nature Reviews …, 2015 - nature.com
High-throughput DNA sequencing has proven invaluable for investigating diverse
environmental and host-associated microbial communities. In this Review, we discuss emerging …

[PDF][PDF] Lactobacillus-deficient cervicovaginal bacterial communities are associated with increased HIV acquisition in young South African women

C Gosmann, SA Handley, M Farcasanu, G Abu-Ali… - Immunity, 2017 - cell.com
Elevated inflammation in the female genital tract is associated with increased HIV risk.
Cervicovaginal bacteria modulate genital inflammation; however, their role in HIV susceptibility …

Assessment of variation in microbial community amplicon sequencing by the Microbiome Quality Control (MBQC) project consortium

R Sinha, G Abu-Ali, E Vogtmann, AA Fodor… - Nature …, 2017 - nature.com
In order for human microbiome studies to translate into actionable outcomes for health, meta-analysis
of reproducible data from population-scale cohorts is needed. Achieving sufficient …

Stability of the human faecal microbiome in a cohort of adult men

RS Mehta, GS Abu-Ali, DA Drew, J Lloyd-Price… - Nature …, 2018 - nature.com
Characterizing the stability of the gut microbiome is important to exploit it as a therapeutic
target and diagnostic biomarker. We metagenomically and metatranscriptomically sequenced …

bioBakery: a meta'omic analysis environment

LJ McIver, G Abu-Ali, EA Franzosa, R Schwager… - …, 2018 - academic.oup.com
bioBakery is a meta’omic analysis environment and collection of individual software tools with
the capacity to process raw shotgun sequencing data into actionable microbial community …

Metatranscriptome of human faecal microbial communities in a cohort of adult men

GS Abu-Ali, RS Mehta, J Lloyd-Price, H Mallick… - Nature …, 2018 - nature.com
The gut microbiome is intimately related to human health, but it is not yet known which
functional activities are driven by specific microorganisms' ecological configurations or …

The role of gut microbiome in the pathogenesis of prostate cancer: a prospective, pilot study

…, CE Barbieri, C Chan, C DuLong, G Abu-Ali… - Urology, 2018 - Elsevier
Objective To elucidate potential biomarkers or mechanistic principles involved with the gut
microbiota and its impact on prostate cancer pathogenesis. Materials and Methods We …

Association between sulfur-metabolizing bacterial communities in stool and risk of distal colorectal cancer in men

…, H Mallick, TK Gerbaba, J Lloyd-Price, G Abu-Ali… - Gastroenterology, 2020 - Elsevier
Background & Aims Sulfur-metabolizing microbes, which convert dietary sources of sulfur into
genotoxic hydrogen sulfide (H 2 S), have been associated with development of colorectal …

Urban transit system microbial communities differ by surface type and interaction with humans and the environment

T Hsu, R Joice, J Vallarino, G Abu-Ali, EM Hartmann… - Msystems, 2016 - Am Soc Microbiol
Public transit systems are ideal for studying the urban microbiome and interindividual community
transfer. In this study, we used 16S amplicon and shotgun metagenomic sequencing to …