User profiles for Galina V Glazko

Galina Glazko

UAMS
Verified email at uams.edu
Cited by 6260

Overcredibility of molecular phylogenies obtained by Bayesian phylogenetics

Y Suzuki, GV Glazko, M Nei - Proceedings of the National …, 2002 - National Acad Sciences
Bayesian phylogenetics has recently been proposed as a powerful method for inferring
molecular phylogenies, and it has been reported that the mammalian and some plant …

Origin of a substantial fraction of human regulatory sequences from transposable elements

IK Jordan, IB Rogozin, GV Glazko, EV Koonin - TRENDS in Genetics, 2003 - cell.com
Transposable elements (TEs) are abundant in mammalian genomes and have potentially
contributed to their hosts' evolution by providing novel regulatory or coding sequences. We …

Estimation of divergence times for major lineages of primate species

GV Glazko, M Nei - Molecular biology and evolution, 2003 - academic.oup.com
Although the phylogenetic relationships of major lineages of primate species are relatively
well established, the times of divergence of these lineages as estimated by molecular data …

Diversity and function of adaptive immune receptors in a jawless vertebrate

MN Alder, IB Rogozin, LM Iyer, GV Glazko, MD Cooper… - Science, 2005 - science.org
Instead of the immunoglobulin-type antigen receptors of jawed vertebrates, jawless fish have
variable lymphocyte receptors (VLRs), which consist of leucine-rich repeat (LRR) modules. …

Evolution and diversification of lamprey antigen receptors: evidence for involvement of an AID-APOBEC family cytosine deaminase

IB Rogozin, LM Iyer, L Liang, GV Glazko, VG Liston… - Nature …, 2007 - nature.com
The variable lymphocyte receptors (VLRs) of jawless vertebrates such as lamprey and
hagfish are composed of highly diverse modular leucine-rich repeats. Each lymphocyte …

[HTML][HTML] Statistical inference and reverse engineering of gene regulatory networks from observational expression data

F Emmert-Streib, GV Glazko, G Altay… - Frontiers in …, 2012 - frontiersin.org
In this paper, we present a systematic and conceptual overview of methods for inferring
gene regulatory networks from observational gene expression data. Further, we discuss two …

Unite and conquer: univariate and multivariate approaches for finding differentially expressed gene sets

GV Glazko, F Emmert-Streib - Bioinformatics, 2009 - academic.oup.com
Motivation: Recently, many univariate and several multivariate approaches have been suggested
for testing differential expression of gene sets between different phenotypes. However, …

[HTML][HTML] Pathway analysis of expression data: deciphering functional building blocks of complex diseases

F Emmert-Streib, GV Glazko - PLoS computational biology, 2011 - journals.plos.org
Identification of differentially expressed pathways from expression data is an important
problem because it allows us to gain insights into the functional working mechanism of cells …

Network biology: a direct approach to study biological function

F Emmert‐Streib, GV Glazko - Wiley Interdisciplinary Reviews …, 2011 - Wiley Online Library
In this paper we discuss the dualism of gene networks and their role in systems biology. We
argue that gene networks (1) can serve as a conceptual framework, forming a fundamental …

A significant fraction of conserved noncoding DNA in human and mouse consists of predicted matrix attachment regions

GV Glazko, EV Koonin, IB Rogozin, SA Shabalina - Trends in Genetics, 2003 - cell.com
Noncoding DNA in the human–mouse orthologous intergenic regions contains ‘islands' of
conserved sequences, the functions of which remain largely unknown. We hypothesized that …