DNA methylation on N6-adenine in mammalian embryonic stem cells
It has been widely accepted that 5-methylcytosine is the only form of DNA methylation in
mammalian genomes. Here we identify N 6 -methyladenine as another form of DNA …
mammalian genomes. Here we identify N 6 -methyladenine as another form of DNA …
Genome-wide mapping of methylated adenine residues in pathogenic Escherichia coli using single-molecule real-time sequencing
G Fang, D Munera, DI Friedman, A Mandlik… - Nature …, 2012 - nature.com
Single-molecule real-time (SMRT) DNA sequencing allows the systematic detection of
chemical modifications such as methylation but has not previously been applied on a genome-…
chemical modifications such as methylation but has not previously been applied on a genome-…
Annotating non-coding regions of the genome
Most of the human genome consists of non-protein-coding DNA. Recently, progress has
been made in annotating these non-coding regions through the interpretation of functional …
been made in annotating these non-coding regions through the interpretation of functional …
[HTML][HTML] Additively manufactured scaffolds for bone tissue engineering and the prediction of their mechanical behavior: A review
Additive manufacturing (AM), nowadays commonly known as 3D printing, is a revolutionary
materials processing technology, particularly suitable for the production of low-volume parts …
materials processing technology, particularly suitable for the production of low-volume parts …
[HTML][HTML] Deciphering bacterial epigenomes using modern sequencing technologies
J Beaulaurier, EE Schadt, G Fang - Nature Reviews Genetics, 2019 - nature.com
Prokaryotic DNA contains three types of methylation: N6-methyladenine, N4-methylcytosine
and 5-methylcytosine. The lack of tools to analyse the frequency and distribution of …
and 5-methylcytosine. The lack of tools to analyse the frequency and distribution of …
[HTML][HTML] KBase: the United States department of energy systems biology knowledgebase
Although similar integrative tools exist (Supplementary Note 2), no other open platform
shares all KBase’s features, which include the following:(i) comprehensive support for data …
shares all KBase’s features, which include the following:(i) comprehensive support for data …
Alkali and ion exchange co-modulation strategies to design magnetic–dielectric synergistic nano-absorbers for tailoring microwave absorption
Y Wu, S Tan, T Zhang, M Zhou, G Fang, G Ji - Nano Research, 2023 - Springer
Alkali and Co 2+ co-modulation has seldom been investigated as a prospective strategy to
achieve high-efficient microwave absorbing (MA) materials. In this work, a new alkali and Co …
achieve high-efficient microwave absorbing (MA) materials. In this work, a new alkali and Co …
Coping with cold: the genome of the versatile marine Antarctica bacterium Pseudoalteromonas haloplanktis TAC125
A considerable fraction of life develops in the sea at temperatures lower than 15C. Little is
known about the adaptive features selected under those conditions. We present the analysis …
known about the adaptive features selected under those conditions. We present the analysis …
[HTML][HTML] Thrombocidins, microbicidal proteins from human blood platelets, are C-terminal deletion products of CXC chemokines
…, SAJ Zaat, J Meeldijk, PA van Veelen, G Fang… - Journal of Biological …, 2000 - ASBMB
Antibacterial proteins are components of the innate immune system found in many organisms
and produced by a variety of cell types. Human blood platelets contain a number of …
and produced by a variety of cell types. Human blood platelets contain a number of …
[HTML][HTML] Phenotypic differences in hiPSC NPCs derived from patients with schizophrenia
Consistent with recent reports indicating that neurons differentiated in vitro from human-induced
pluripotent stem cells (hiPSCs) are immature relative to those in the human brain, gene …
pluripotent stem cells (hiPSCs) are immature relative to those in the human brain, gene …