Copy Number Variation (CNV) at the 1q21.1 locus is associated with a range of
neurodevelopmental and psychiatric disorders in humans, including abnormalities in head size and …

Neuroinflammation is recognised as one of the potential mechanisms mediating the onset of
a broad range of psychiatric disorders and may contribute to nonresponsiveness to current …

The development of functional polymer parts with complex geometrical shape has been
possible through additive manufacturing. In this research work, the issues such as warping, …

Coordinated programs of gene expression drive brain development. It is unclear which
transcriptional programs, in which cell-types, are affected in neuropsychiatric disorders such as …

Copy number variants (CNVs), involving duplication or deletion of susceptible intervals of the
human genome, underlie a range of neurodevelopmental and neuropsychiatric disorders. …

• Inguinal disruption is an overuse injury associated with sports or activities that involve
twisting, sprinting, and kicking movements• Consider inguinal disruption in athletes presenting …

Human pluripotent stem cell (hPSC)-derived neurons provide a valuable platform for
modeling altered neuronal physiology, development, and function that contribute to …

While many genetic risk factors are currently associated with autism spectrum disorder (ASD),
no single mutation accounts for more than a minor fraction of cases. Understanding how …

Brain development requires a complex choreography of cell proliferation, specialisation,
migration and network formation, guided by the activation and repression of gene expression …

Genetic studies robustly implicate perturbation of DLG2-scaffolded mature postsynaptic
signalling complexes in schizophrenia. Here we study in vitro cortical differentiation of DLG2-/- …