INTRODUCTION Dendritic cells (DCs) and monocytes consist of multiple specialized
subtypes that play a central role in pathogen sensing, phagocytosis, and antigen presentation. …

Abstract Analysis of human blood immune cells provides insights into the coordinated
response to viral infections such as severe acute respiratory syndrome coronavirus 2, which …

It is not fully understood why COVID-19 is typically milder in children 1 , 2 – 3 . Here, to examine
the differences between children and adults in their response to SARS-CoV-2 infection, …

INTRODUCTION Human skin provides vital protection from water loss and from external insult
through structural adaptations and interplay with the innate and adaptive immune systems…

Hepatitis B virus (HBV) causes chronic infection in more than 350 million people worldwide.
It replicates in hepatocytes but is non-cytopathic; liver damage is thought to be immune …

INTRODUCTION The thymus is the critical organ for T cell development and T cell receptor (TCR)
repertoire formation, which shapes the landscape of adaptive immunity. T cell …

Definitive haematopoiesis in the fetal liver supports self-renewal and differentiation of
haematopoietic stem cells and multipotent progenitors (HSC/MPPs) but remains poorly defined in …

Longitudinal analyses of the innate immune system, including the earliest time points, are
essential to understand the immunopathogenesis and clinical course of coronavirus disease (…

Antiviral T cell responses in hepatotropic viral infections such as hepatitis B virus (HBV) are
profoundly diminished and prone to apoptotic deletion. In this study, we investigate whether …

BACKGROUND & AIMS: Hepatitis C virus (HCV) infection leads to progressive liver disease
and is associated with a variety of extrahepatic syndromes, including central nervous …