To the Editor—Rapid advances in DNA-sequencing and bioinformatics technologies in the
past two decades have substantially improved understanding of the microbial world. This …

To the Editor: High-throughput sequencing is revolutionizing microbial ecology studies.
Efforts like the Human Microbiome Projects 1 and the US National Ecological Observatory …

Background Taxonomic classification of marker-gene sequences is an important step in
microbiome analysis. Results We present q2-feature-classifier ( https://github.com/qiime2/q2-…

The chemokine receptor 5 (CKR5) protein serves as a secondary receptor on CD4 + T
lymphocytes for certain strains of human immunodeficiency virus-type 1 (HIV-1). The CKR5 …

The critical role of chemokine receptors (CCR5 and CXCR4) in human immunodeficiency
virus–type 1 (HIV-1) infection and pathogenesis prompted a search for polymorphisms in other …

Objective. In the sanroque mouse model of lupus, pathologic germinal centers (GCs) arise
due to increased numbers of follicular helper T (Tfh) cells, resulting in high-affinity anti–double…

We report a high-quality draft of the genome sequence of the grey, short-tailed opossum (Monodelphis
domestica). As the first metatherian (‘marsupial’) species to be sequenced, the …

The CCR5-Δ32 deletion obliterates the CCR5 chemokine and the human immunodeficiency
virus (HIV)–1 coreceptor on lymphoid cells, leading to strong resistance against HIV-1 …

More than a billion humans worldwide are predicted to be completely deficient in the fast
skeletal muscle fiber protein α-actinin-3 owing to homozygosity for a premature stop codon …

DNA from ancient human remains provides perspectives on the origin of our species and the
relationship between molecular and morphological variation. We report analysis of mtDNA …