User profiles for Gavin J.B. Elias

Gavin JB Elias

University of Toronto
Verified email at mail.utoronto.ca
Cited by 2827

Deep brain stimulation for stroke: Current uses and future directions

GJB Elias, AA Namasivayam, AM Lozano - Brain stimulation, 2018 - Elsevier
Background Survivors of stroke often experience significant disability and impaired quality
of life related to ongoing maladaptive responses and persistent neurologic deficits. Novel …

Improving safety of MRI in patients with deep brain stimulation devices

A Boutet, CT Chow, K Narang, GJB Elias, C Neudorfer… - Radiology, 2020 - pubs.rsna.org
MRI is a valuable clinical and research tool for patients undergoing deep brain stimulation (DBS).
However, risks associated with imaging DBS devices have led to stringent regulations, …

[HTML][HTML] Predicting optimal deep brain stimulation parameters for Parkinson's disease using functional MRI and machine learning

A Boutet, R Madhavan, GJB Elias, SE Joel… - Nature …, 2021 - nature.com
Commonly used for Parkinson’s disease (PD), deep brain stimulation (DBS) produces
marked clinical benefits when optimized. However, assessing the large number of possible …

[HTML][HTML] A unified connectomic target for deep brain stimulation in obsessive-compulsive disorder

…, A Kibleur, S Treu, H Akram, GJB Elias… - Nature …, 2020 - nature.com
Multiple surgical targets for treating obsessive-compulsive disorder with deep brain stimulation
(DBS) have been proposed. However, different targets may modulate the same neural …

Neuromodulation for the treatment of eating disorders and obesity

DJ Lee, GJB Elias, AM Lozano - Therapeutic advances in …, 2018 - journals.sagepub.com
Eating disorders and obesity adversely affect individuals both medically and psychologically,
leading to reduced life expectancy and poor quality of life. While there exist a number of …

[HTML][HTML] Optimal deep brain stimulation sites and networks for stimulation of the fornix in Alzheimer's disease

…, N Li, N Rajamani, A Boutet, GJB Elias… - Nature …, 2022 - nature.com
Deep brain stimulation (DBS) to the fornix is an investigational treatment for patients with mild
Alzheimer’s Disease. Outcomes from randomized clinical trials have shown that cognitive …

Focused ultrasound thalamotomy location determines clinical benefits in patients with essential tremor

…, E Hlasny, M Llinas, CS Lozano, GJB Elias… - Brain, 2018 - academic.oup.com
Magnetic resonance guided focused ultrasound (MRgFUS) thalamotomy is a novel and
minimally invasive ablative treatment for essential tremor. The size and location of therapeutic …

Probabilistic mapping of deep brain stimulation: insights from 15 years of therapy

GJB Elias, A Boutet, SE Joel, J Germann… - Annals of …, 2021 - Wiley Online Library
Deep brain stimulation (DBS) depends on precise delivery of electrical current to target tissues.
However, the specific brain structures responsible for best outcome are still debated. We …

Bilateral focused ultrasound thalamotomy for essential tremor (BEST‐FUS phase 2 trial)

…, J Germann, A Loh, A Boutet, GJB Elias… - Movement …, 2021 - Wiley Online Library
Background In patients with medically refractory essential tremor, unilateral magnetic
resonance–guided focused ultrasound thalamotomy can improve contralateral tremor. However, …

[HTML][HTML] A high-resolution in vivo magnetic resonance imaging atlas of the human hypothalamic region

C Neudorfer, J Germann, GJB Elias, R Gramer… - Scientific data, 2020 - nature.com
The study of the hypothalamus and its topological changes provides valuable insights into
underlying physiological and pathological processes. Owing to technological limitations, …