Altered eIF4A1 activity promotes translation of highly structured, eIF4A1-dependent oncogene
mRNAs at root of oncogenic translational programmes. It remains unclear how these …

The Hippo pathway is an important regulator of cell growth, proliferation, and migration.
TEAD transcription factors, which lie at the core of the Hippo pathway, are essential for …

Approaches are needed for therapy of the severe acute respiratory syndrome from SARS-CoV-2
coronavirus (COVID-19). Interfering with the interaction of viral antigens with the …

Many subsurface microorganisms couple their metabolism to the reduction or oxidation of
extracellular substrates. For example, anaerobic mineral-respiring bacteria can use external …

Cleavage and polyadenylation specificity factor 6 (CPSF6) is a human protein that binds HIV-1
capsid and mediates nuclear transport and integration targeting of HIV-1 preintegration …

The Vip3 proteins produced during vegetative growth by strains of the bacterium Bacillus
thuringiensis show insecticidal activity against lepidopteran insects with a mechanism of action …

Staphylococcus aureus and Staphylococcus epidermidis are frequently associated with
medical device infections that involve establishment of a bacterial biofilm on the device surface. …

BBK32 is a fibronectin (FN)-binding protein expressed on the cell surface of Borrelia burgdorferi,
the causative agent of Lyme disease. There is conflicting information about where and …

The gastric peptide hormone human PYY 3–36 is a target for the development of therapeutics,
especially for treatment of obesity. The conformation and aggregation behavior of …

Bacterial fibronectin-binding proteins (FnBPs) contain a large intrinsically disordered region
(IDR) that mediates adhesion of bacteria to host tissues, and invasion of host cells, through …