We report severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike ΔH69/V70
in multiple independent lineages, often occurring after acquisition of receptor binding motif …

The progression of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
pandemic in Africa has so far been heterogeneous, and the full impact is not yet well understood…

The gold standard for clinical diagnosis of bacterial lower respiratory infections (LRIs) is
culture, which has poor sensitivity and is too slow to guide early, targeted antimicrobial therapy. …

Investment in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) sequencing
in Africa over the past year has led to a major increase in the number of sequences that have …

Tuberculosis (TB) was once a major killer in Europe, but it is unclear how the strains and
patterns of infection at ‘peak TB’ relate to what we see today. Here we describe 14 genome …

Background Several infectious diseases and therapeutic interventions cause gut microbe
dysbiosis and associated pathology. We characterised the gut microbiome of children exposed …

We present CoronaHiT, a platform and throughput flexible method for sequencing SARS-CoV-2
genomes (≤ 96 on MinION or > 96 on Illumina NextSeq) depending on changing …

Background Bacteria play a suspected role in the development of several cancer types, and
associations between the presence of particular bacteria and prostate cancer have been …

Shotgun metagenomics provides a powerful assumption-free approach to the recovery of
pathogen genomes from contemporary and historical material. We sequenced the …

The COVID-19 pandemic has spread rapidly throughout the world. In the UK, the initial peak
was in April 2020; in the county of Norfolk (UK) and surrounding areas, which has a stable, …