Characterizing the transcriptome of individual cells is fundamental to understanding complex
biological systems. We describe a droplet-based system that enables 3′ mRNA counting …

Haplotyping of human chromosomes is a prerequisite for cataloguing the full repertoire of
genetic variation. We present a microfluidics-based, linked-read sequencing technology that …

Understanding complex tissues requires single-cell deconstruction of gene regulation with
precision and scale. Here, we assess the performance of a massively parallel droplet-based …

Two years ago, we described the first droplet digital PCR (ddPCR) system aimed at empowering
all researchers with a tool that removes the substantial uncertainties associated with …

Measurement of glutathione (GSH) and glutathione disulfide (GSSG) is a crucial tool to
assess cellular redox state. Herein we report a direct approach to determine intracellular GSH …

The quantification of low-molecular mass thiols and disulfides involved in cellular redox
processes is hindered by oxidation or degradation of analytes during conventional sample …

The use of high performance liquid chromatography with acidic potassium permanganate
chemiluminescence detection to screen for antioxidants in complex plant-derived samples …

Two exceedingly stable [Ru(bipy) 3 ] 3+ reagents were prepared by dissolving either [Ru(bipy)
3 ](ClO 4 ) 2 in acetonitrile (containing 0.05 M HClO 4 ) or [Ru(bipy) 3 ]Cl 2 ·6H 2 O in 95:5 …

The antioxidant profiles of various espresso coffees were established using HPLC with UV-absorbance
detection and two rapid, simultaneous, on-line chemical assays that enabled the …

We have conducted a comprehensive comparative study of Ru(bipy) 3 2+ , Ru(bipy) 2 (phen)
2+ , Ru(bipy)(phen) 2 2+ , and Ru(phen) 3 2+ as chemiluminescence and …