User profiles for George BJ Busby

George Busby

Chief Scientific Officer and Co-founder, Allelica Inc
Verified email at allelica.com
Cited by 3940

Ancient human genomes suggest three ancestral populations for present-day Europeans

…, J Bene, F Berrada, CM Bravi, F Brisighelli, GBJ Busby… - Nature, 2014 - nature.com
We sequenced the genomes of a ∼7,000-year-old farmer from Germany and eight ∼8,000-year-old
hunter-gatherers from Luxembourg and Sweden. We analysed these and other …

A genetic atlas of human admixture history

G Hellenthal, GBJ Busby, G Band, JF Wilson, C Capelli… - science, 2014 - science.org
Modern genetic data combined with appropriate statistical methods have the potential to
contribute substantially to our understanding of human history. We have developed an …

Resistance to malaria through structural variation of red blood cell invasion receptors

EM Leffler, G Band, GBJ Busby, K Kivinen, QS Le… - Science, 2017 - science.org
INTRODUCTION Malaria parasites cause human disease by invading and replicating inside
red blood cells. In the case of Plasmodium falciparum, this can lead to severe forms of …

[HTML][HTML] Unravelling the hidden ancestry of American admixed populations

F Montinaro, GBJ Busby, VL Pascali, S Myers… - Nature …, 2015 - nature.com
The movement of people into the Americas has brought different populations into contact, and
contemporary American genomes are the product of a range of complex admixture events. …

Admixture into and within sub-Saharan Africa

GBJ Busby, G Band, Q Si Le, M Jallow, E Bougama… - elife, 2016 - elifesciences.org
10.7554/eLife.15266.001 Similarity between two individuals in the combination of genetic
markers along their chromosomes indicates shared ancestry and can be used to identify …

The peopling of Europe and the cautionary tale of Y chromosome lineage R-M269

GBJ Busby, F Brisighelli… - … of the Royal …, 2012 - royalsocietypublishing.org
Recently, the debate on the origins of the major European Y chromosome haplogroup
R1b1b2-M269 has reignited, and opinion has moved away from Palaeolithic origins to the notion …

[HTML][HTML] An open dataset of Plasmodium falciparum genome variation in 7,000 worldwide samples

…, T Bousema, O Branch, PC Bull, GBJ Busby… - Wellcome Open …, 2021 - ncbi.nlm.nih.gov
A major obstacle to malaria elimination is the great capacity of the parasite and vector
populations to evolve in response to malaria control interventions. The widespread use of …

[PDF][PDF] The role of recent admixture in forming the contemporary West Eurasian genomic landscape

GBJ Busby, G Hellenthal, F Montinaro, S Tofanelli… - Current biology, 2015 - cell.com
Over the past few years, studies of DNA isolated from human fossils and archaeological
remains have generated considerable novel insight into the history of our species. Several …

Complex ancient genetic structure and cultural transitions in southern African populations

F Montinaro, GBJ Busby, M Gonzalez-Santos… - Genetics, 2017 - academic.oup.com
The characterization of the structure of southern African populations has been the subject of
numerous genetic, medical, linguistic, archaeological, and anthropological investigations. …

Static and moving frontiers: the genetic landscape of Southern African Bantu-speaking populations

…, S Bertoncini, C Batini, GBJ Busby… - Molecular biology …, 2015 - academic.oup.com
A consensus on Bantu-speaking populations being genetically similar has emerged in the
last few years, but the demographic scenarios associated with their dispersal are still a matter …