[HTML][HTML] Size-dependent endocytosis of nanoparticles
Recent advances in nanotechnology have stimulated novel applications in biomedicine
where nanoparticles (NPs) are used to achieve drug delivery and photodynamic therapy. In …
where nanoparticles (NPs) are used to achieve drug delivery and photodynamic therapy. In …
Refractive index maps and membrane dynamics of human red blood cells parasitized by Plasmodium falciparum
…, G Popescu, G Lykotrafitis… - Proceedings of the …, 2008 - National Acad Sciences
Parasitization by malaria-inducing Plasmodium falciparum leads to structural, biochemical,
and mechanical modifications to the host red blood cells (RBCs). To study these modifications…
and mechanical modifications to the host red blood cells (RBCs). To study these modifications…
Cytoskeletal dynamics of human erythrocyte
The human erythrocyte (red blood cell, RBC) demonstrates extraordinary ability to undergo
reversible large deformation and fluidity. Such mechanical response cannot be consistently …
reversible large deformation and fluidity. Such mechanical response cannot be consistently …
[PDF][PDF] Erythrocyte membrane model with explicit description of the lipid bilayer and the spectrin network
H Li, G Lykotrafitis - Biophysical journal, 2014 - cell.com
The membrane of the red blood cell (RBC) consists of spectrin tetramers connected at actin
junctional complexes, forming a two-dimensional (2D) sixfold triangular network anchored to …
junctional complexes, forming a two-dimensional (2D) sixfold triangular network anchored to …
Sickle cell trait human erythrocytes are significantly stiffer than normal
JL Maciaszek, G Lykotrafitis - Journal of biomechanics, 2011 - Elsevier
Atomic force microscopy (AFM) allows for high-resolution topography studies of biological
cells and measurement of their mechanical properties in physiological conditions. In this work, …
cells and measurement of their mechanical properties in physiological conditions. In this work, …
One-particle-thick, solvent-free, coarse-grained model for biological and biomimetic fluid membranes
Biological membranes are involved in numerous intriguing biophysical and biological cellular
phenomena of different length scales, ranging from nanoscale raft formation, vesiculation, …
phenomena of different length scales, ranging from nanoscale raft formation, vesiculation, …
Agent-based modeling of a multi-room multi-floor building emergency evacuation
V Ha, G Lykotrafitis - Physica A: Statistical Mechanics and its Applications, 2012 - Elsevier
Panic during emergency building evacuation can cause crowd stampede, resulting in
serious injuries and casualties. Agent-based methods have been successfully employed to …
serious injuries and casualties. Agent-based methods have been successfully employed to …
Biomechanics and biorheology of red blood cells in sickle cell anemia
… Li and Lykotrafitis simulated the biomechanical properties of HbS polymer fibers via two
different coarse-grained HbS fiber models, demonstrating the significant role of fiber frustration …
different coarse-grained HbS fiber models, demonstrating the significant role of fiber frustration …
[HTML][HTML] Modeling of the axon membrane skeleton structure and implications for its mechanical properties
…, DM Pierce, AV Tzingounis, G Lykotrafitis - PLoS computational …, 2017 - journals.plos.org
Super-resolution microscopy recently revealed that, unlike the soma and dendrites, the axon
membrane skeleton is structured as a series of actin rings connected by spectrin filaments …
membrane skeleton is structured as a series of actin rings connected by spectrin filaments …
[PDF][PDF] Two-component coarse-grained molecular-dynamics model for the human erythrocyte membrane
H Li, G Lykotrafitis - Biophysical journal, 2012 - cell.com
We present a two-component coarse-grained molecular-dynamics model for simulating the
erythrocyte membrane. The proposed model possesses the key feature of combing the lipid …
erythrocyte membrane. The proposed model possesses the key feature of combing the lipid …