[HTML][HTML] Size-dependent endocytosis of nanoparticles

S Zhang, J Li, G Lykotrafitis, G Bao… - … (Deerfield Beach, Fla.), 2009 - ncbi.nlm.nih.gov
Recent advances in nanotechnology have stimulated novel applications in biomedicine
where nanoparticles (NPs) are used to achieve drug delivery and photodynamic therapy. In …

Refractive index maps and membrane dynamics of human red blood cells parasitized by Plasmodium falciparum

…, G Popescu, G Lykotrafitis… - Proceedings of the …, 2008 - National Acad Sciences
Parasitization by malaria-inducing Plasmodium falciparum leads to structural, biochemical,
and mechanical modifications to the host red blood cells (RBCs). To study these modifications…

Cytoskeletal dynamics of human erythrocyte

J Li, G Lykotrafitis, M Dao… - Proceedings of the …, 2007 - National Acad Sciences
The human erythrocyte (red blood cell, RBC) demonstrates extraordinary ability to undergo
reversible large deformation and fluidity. Such mechanical response cannot be consistently …

[PDF][PDF] Erythrocyte membrane model with explicit description of the lipid bilayer and the spectrin network

H Li, G Lykotrafitis - Biophysical journal, 2014 - cell.com
The membrane of the red blood cell (RBC) consists of spectrin tetramers connected at actin
junctional complexes, forming a two-dimensional (2D) sixfold triangular network anchored to …

Sickle cell trait human erythrocytes are significantly stiffer than normal

JL Maciaszek, G Lykotrafitis - Journal of biomechanics, 2011 - Elsevier
Atomic force microscopy (AFM) allows for high-resolution topography studies of biological
cells and measurement of their mechanical properties in physiological conditions. In this work, …

One-particle-thick, solvent-free, coarse-grained model for biological and biomimetic fluid membranes

H Yuan, C Huang, J Li, G Lykotrafitis, S Zhang - Physical review E, 2010 - APS
Biological membranes are involved in numerous intriguing biophysical and biological cellular
phenomena of different length scales, ranging from nanoscale raft formation, vesiculation, …

Agent-based modeling of a multi-room multi-floor building emergency evacuation

V Ha, G Lykotrafitis - Physica A: Statistical Mechanics and its Applications, 2012 - Elsevier
Panic during emergency building evacuation can cause crowd stampede, resulting in
serious injuries and casualties. Agent-based methods have been successfully employed to …

Biomechanics and biorheology of red blood cells in sickle cell anemia

X Li, M Dao, G Lykotrafitis, GE Karniadakis - Journal of biomechanics, 2017 - Elsevier
… Li and Lykotrafitis simulated the biomechanical properties of HbS polymer fibers via two
different coarse-grained HbS fiber models, demonstrating the significant role of fiber frustration …

[HTML][HTML] Modeling of the axon membrane skeleton structure and implications for its mechanical properties

…, DM Pierce, AV Tzingounis, G Lykotrafitis - PLoS computational …, 2017 - journals.plos.org
Super-resolution microscopy recently revealed that, unlike the soma and dendrites, the axon
membrane skeleton is structured as a series of actin rings connected by spectrin filaments …

[PDF][PDF] Two-component coarse-grained molecular-dynamics model for the human erythrocyte membrane

H Li, G Lykotrafitis - Biophysical journal, 2012 - cell.com
We present a two-component coarse-grained molecular-dynamics model for simulating the
erythrocyte membrane. The proposed model possesses the key feature of combing the lipid …