The history of the American West is being transformed by exciting new ideas, new questions,
new scholarship. For many years this field was dominated by popular images of the lone …

We present a proteogenomic study of 108 human papilloma virus (HPV)-negative head and
neck squamous cell carcinomas (HNSCCs). Proteomic analysis systematically catalogs …

The integration of mass spectrometry-based proteomics with next-generation DNA and RNA
sequencing profiles tumors more comprehensively. Here this "proteogenomics" approach …

Many oncogenic insults deregulate RNA splicing, often leading to hypersensitivity of tumors
to spliceosome-targeted therapies (STTs). However, the mechanisms by which STTs …

Proteogenomic analysis of triple-negative breast tumors revealed a complex landscape of
chemotherapy response associations, including a 19q13.31–33 somatic deletion encoding …

Staphylococcal leukocidin pores are formed by the obligatory interaction of two distinct
polypeptides, one of class F and one of class S, making them unique in the family of β‐barrel pore…

Background: Pulmonary hypertension (PH) in adults with sickle cell disease (SCD) is
associated with early mortality, but no prior studies have evaluated quantitative relationships of …

Cancer proteogenomics promises new insights into cancer biology and treatment efficacy by
integrating genomics, transcriptomics and protein profiling including modifications by mass …

This paper, written for oral presentation, was read at the Symposium on" The Relations
between Byzantium and the Arabs" at Dumbarton Oaks in May 1963. It is reproduced here …

Despite substantial advances in targeting mutant KRAS, tumor resistance to KRAS inhibitors
(KRASi) remains a major barrier to progress. Here, we report proteostasis reprogramming …