There are adaptive T-cell and antibody autoimmune responses to myelin-derived peptides
in multiple sclerosis (MS) and to aquaporin-4 (AQP4) in neuromyelitis optica spectrum …

The identification of activated T-lymphocytes restricted to myelin-derived immunogenic
peptides in multiple sclerosis (MS) and aquaporin-4 water channel in neuromyelitis optica (NMO) …

Immunotherapeutic approaches have revolutionized the treatment of several diseases such
as cancer. The main goal of immunotherapy for cancer is to modulate the anti-tumor immune …

Background and objective Diffuse intrinsic pontine glioma (DIPG) is a lethal brainstem tumor
in children. Dendritic cells (DCs) have T-cell stimulatory capacity and, therefore, potential …

This article is part of the Dendritic Cell Guidelines article series, which provides a collection
of state‐of‐the‐art protocols for the preparation, phenotype analysis by flow cytometry, …

Imbalanced immune responses are a prominent hallmark of cancer and autoimmunity. Myeloid
cells can be overly suppressive, inhibiting protective immune responses or inactive not …

Plasmacytoid dendritic cells (pDCs) and type 2 conventional dendritic cells (cDC2s) are
currently under evaluation for use in cancer vaccines. Although both DC subsets can activate …

Cancer immunotherapies have induced long-lasting responses in cancer patients including
those with melanoma and head and neck squamous cell carcinoma (HNSCC). However, the …

Current treatment for patients with non-small-cell lung cancer (NSCLC) is suboptimal since
therapy is only effective in a minority of patients and does not always induce a long-lasting …

Dendritic cells (DCs) are key regulators of the immune system that shape T cell responses.
Regulation of T cell induction by DCs may occur via the intracellular enzyme indoleamine 2,3…