The functional and molecular similarities and distinctions between human and murine astrocytes
are poorly understood. Here, we report the development of an immunopanning method …

✓ The purpose of this study was to determine whether patients with minor head injury experience
impairments in cerebral autoregulation. Twenty-nine patients with minor head injuries …

Microglia, the brain's resident macrophages, are dynamic CNS custodians with surprising
origins in the extra-embryonic yolk sac. The consequences of their distinct ontogeny are …

The specific function of microglia, the tissue resident macrophages of the brain and spinal
cord, has been difficult to ascertain because of a lack of tools to distinguish microglia from …

Understanding the control of the optical and plasmonic properties of unique nanosystems—gold
nanostars—both experimentally and theoretically permits superior design and …

With the passage of the Sarbanes-Oxley Act in the United States in 2002, and an ever-increasing
corporate focus on ensuring prudent returns on technology investments, the notion of …

Smoothened (SMO) inhibitors recently entered clinical trials for sonic-hedgehog-driven
medulloblastoma (SHH-MB). Clinical response is highly variable. To understand the mechanism(…

Self-organizing neural organoids represent a promising in vitro platform with which to model
human development and disease 1 , 2 , 3 , 4 – 5 . However, organoids lack the connectivity …

While use of advanced visualization in radiology is instrumental in diagnosis and
communication with referring clinicians, there is an unmet need to render Digital Imaging and …

Objectives: A relationship between reduced brain tissue oxygenation and poor outcome
following severe traumatic brain injury has been reported in observational studies. We designed …