An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow
…, S Rößner, F Koch, N Romani, G Schuler - Journal of …, 1999 - Elsevier
As dendritic cells (DC) are rare populations in all organs, their generation from hematopoietic
precursors in large quantities has proven critical to study their biology. From murine bone …
precursors in large quantities has proven critical to study their biology. From murine bone …
Proliferating dendritic cell progenitors in human blood.
…, PO Fritsch, RM Steinman, G Schuler - The Journal of …, 1994 - rupress.org
CD34+ cells in human cord blood and marrow are known to give rise to dendritic cells (DC),
as well as to other myeloid lineages. CD34+ cells are rare in adult blood, however, making it …
as well as to other myeloid lineages. CD34+ cells are rare in adult blood, however, making it …
Induction of Interleukin 10–Producing, Nonproliferating Cd4+ T Cells with Regulatory Properties by Repetitive Stimulation with Allogeneic Immature Human Dendritic …
H Jonuleit, E Schmitt, G Schuler, J Knop… - The Journal of …, 2000 - rupress.org
The functional properties of dendritic cells (DCs) are strictly dependent on their maturational
state. To analyze the influence of the maturational state of DCs on priming and …
state. To analyze the influence of the maturational state of DCs on priming and …
Immature, semi-mature and fully mature dendritic cells: which signals induce tolerance or immunity?
MB Lutz, G Schuler - Trends in immunology, 2002 - cell.com
Dendritic cells (DCs) are currently divided into tolerogenic immature and immunogenic mature
differentiation stages. However, recent findings challenge this model by reporting mature …
differentiation stages. However, recent findings challenge this model by reporting mature …
Vaccination with mage-3A1 peptide–pulsed mature, monocyte-derived dendritic cells expands specific cytotoxic T cells and induces regression of some metastases in …
…, RM Steinman, A Enk, E Kämpgen, G Schuler - The Journal of …, 1999 - rupress.org
Dendritic cells (DCs) are considered to be promising adjuvants for inducing immunity to cancer.
We used mature, monocyte-derived DCs to elicit resistance to malignant melanoma. The …
We used mature, monocyte-derived DCs to elicit resistance to malignant melanoma. The …
Murine epidermal Langerhans cells mature into potent immunostimulatory dendritic cells in vitro.
G Schuler, RM Steinman - The Journal of experimental medicine, 1985 - rupress.org
Murine epidermal Langerhans cells (LC) have been studied in tissue culture and compared
to spleen dendritic cells (DC). LC comprised 3% of the starting cell suspensions and were …
to spleen dendritic cells (DC). LC comprised 3% of the starting cell suspensions and were …
Ex Vivo Isolation and Characterization of Cd4+Cd25+ T Cells with Regulatory Properties from Human Blood
…, H Plottner, S Berchtold, T Berger, G Schuler - The Journal of …, 2001 - rupress.org
It has been known for years that rodents harbor a unique population of CD4 + CD25 + “professional”
regulatory/suppressor T cells that is crucial for the prevention of spontaneous …
regulatory/suppressor T cells that is crucial for the prevention of spontaneous …
Generation of mature dendritic cells from human blood An improved method with special regard to clinical applicability
…, E Kämpgen, B Eibl, D Niederwieser, G Schuler - Journal of …, 1996 - Elsevier
Two methods to generate human dendritic cells from hematopoietic precursor cells in peripheral
blood have recently been published. One approach utilizes the rare CD34 + precursors …
blood have recently been published. One approach utilizes the rare CD34 + precursors …
[HTML][HTML] Dendritic cells as vectors for therapy
…, B Schuler-Thurner, AK Palucka, G Schuler - Cell, 2001 - cell.com
Vaccines against infectious diseases are the success story of immunology. They have
eradicated smallpox and spared countless people from tetanus, measles, polio, and hepatitis. …
eradicated smallpox and spared countless people from tetanus, measles, polio, and hepatitis. …
High level IL-12 production by murine dendritic cells: upregulation via MHC class II and CD40 molecules and downregulation by IL-4 and IL-10.
…, C Heufler, E Kämpgen, N Romani, G Schuler - The Journal of …, 1996 - rupress.org
We have shown previously that dendritic cells (DC) produce IL-12 upon interaction with CD4+
T cells. Here we ask how this IL-12 production is induced and regulated. Quantitative PCR …
T cells. Here we ask how this IL-12 production is induced and regulated. Quantitative PCR …