There is a rapidly expanding literature on the in vitro antiviral activity of drugs that may be
repurposed for therapy or chemoprophylaxis against severe acute respiratory syndrome‐…

Background Ivermectin is being considered for mass drug administration for malaria due to
its ability to kill mosquitoes feeding on recently treated individuals. However, standard, single …

PCR of upper respiratory specimens is the diagnostic standard for severe acute respiratory
syndrome coronavirus 2 infection. However, saliva sampling is an easy alternative to nasal …

Background Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) has been
declared a global pandemic and urgent treatment and prevention strategies are needed. …

Lymphatic filariasis (LF) and onchocerciasis are priority neglected tropical diseases targeted
for elimination. The only safe drug treatment with substantial curative activity against the …

There is an urgent global need for a safe macrofilaricide drug to accelerate elimination of
the neglected tropical diseases onchocerciasis and lymphatic filariasis. From an anti-infective …

Onchocerciasis and lymphatic filariasis are two neglected tropical diseases that together
affect ∼157 million people and inflict severe disability. Both diseases are caused by parasitic …

Mycobacterium tuberculosis cytochrome bd quinol oxidase (cyt bd), the alternative terminal
oxidase of the respiratory chain, has been identified as playing a key role during chronic …

The rapidly growing COVID-19 pandemic is the most serious global health crisis since the “Spanish
flu” of 1918. There is currently no proven effective drug treatment or prophylaxis for …

Background Ivermectin is a potential new vector control tool to reduce malaria transmission.
Mosquitoes feeding on a bloodmeal containing ivermectin have a reduced lifespan, …