User profiles for Gianluca Grenci

Gianluca Grenci

Senior Research Scientist, Mechanobiology Institute (MBI) - National University of …
Verified email at nus.edu.sg
Cited by 3194

Chemical vapour deposition of zeolitic imidazolate framework thin films

I Stassen, M Styles, G Grenci, HV Gorp… - Nature materials, 2016 - nature.com
Integrating metal–organic frameworks (MOFs) in microelectronics has disruptive potential
because of the unique properties of these microporous crystalline materials. Suitable film …

Automated high-speed 3D imaging of organoid cultures with multi-scale phenotypic quantification

A Beghin, G Grenci, G Sahni, S Guo, H Rajendiran… - Nature …, 2022 - nature.com
Current imaging approaches limit the ability to perform multi-scale characterization of three-dimensional
(3D) organotypic cultures (organoids) in large numbers. Here, we present an …

3D high-and super-resolution imaging using single-objective SPIM

R Galland, G Grenci, A Aravind, V Viasnoff, V Studer… - Nature …, 2015 - nature.com
Single-objective selective-plane illumination microscopy (soSPIM) is achieved with
micromirrored cavities combined with a laser beam–steering unit installed on a standard inverted …

Cell response to substrate rigidity is regulated by active and passive cytoskeletal stress

BL Doss, M Pan, M Gupta, G Grenci… - Proceedings of the …, 2020 - National Acad Sciences
Morphogenesis, tumor formation, and wound healing are regulated by tissue rigidity. Focal
adhesion behavior is locally regulated by stiffness; however, how cells globally adapt, detect, …

Expansion of patient-derived circulating tumor cells from liquid biopsies using a CTC microfluidic culture device

BL Khoo, G Grenci, YB Lim, SC Lee, J Han, CT Lim - Nature protocols, 2018 - nature.com
The development of personalized cancer therapy depends on a robust system to monitor
the patient's individual response to anticancer treatment. Anticancer drug efficacy has been …

Liquid biopsy and therapeutic response: Circulating tumor cell cultures for evaluation of anticancer treatment

BL Khoo, G Grenci, T Jing, YB Lim, SC Lee… - Science …, 2016 - science.org
The lack of a robust anticancer drug screening system to monitor patients during treatment
delays realization of personalized treatment. We demonstrate an efficient approach to …

Combining UV lithography and an imprinting technique for patterning metal-organic frameworks.

CM Doherty, G Grenci, R Riccò, JI Mardel… - … (Deerfield Beach, Fla …, 2013 - europepmc.org
Thin metal-organic framework (MOF) films are patterned using UV lithography and an imprinting
technique. A UV lithographed SU-8 film is imprinted onto a film of MOF powder forming …

Hyperspectral infrared microscopy with visible light

AV Paterova, SM Maniam, H Yang, G Grenci… - Science …, 2020 - science.org
Hyperspectral microscopy is an imaging technique that provides spectroscopic information
with high spatial resolution. When applied in the relevant wavelength region, such as in the …

[HTML][HTML] Circulating Tumor Cell cluster phenotype allows monitoring response to treatment and predicts survival

…, D Koppaka, A Anand, B Deb, G Grenci… - Scientific Reports, 2019 - nature.com
Circulating tumor cells (CTCs) are putative markers of tumor prognosis and may serve to
evaluate patient’s response to chemotherapy. CTCs are often detected as single cells but …

Acceleration of neuronal precursors differentiation induced by substrate nanotopography

E Migliorini, G Grenci, J Ban, A Pozzato… - Biotechnology and …, 2011 - Wiley Online Library
Embryonic stem (ES) cell differentiation in specific cell lineages is a major issue in cell
biology particularly in regenerative medicine. Differentiation is usually achieved by using …