[HTML][HTML] A microfluidic platform integrating functional vascularized organoids-on-chip
…, C Laporte, A Pitaval, TS Bah, G Pomeranz… - Nature …, 2024 - nature.com
The development of vascular networks in microfluidic chips is crucial for the long-term culture
of three-dimensional cell aggregates such as spheroids, organoids, tumoroids, or tissue …
of three-dimensional cell aggregates such as spheroids, organoids, tumoroids, or tissue …
[HTML][HTML] Diverse species-specific phenotypic consequences of loss of function sorting nexin 14 mutations
D Bryant, M Seda, E Peskett, C Maurer, G Pomeranz… - Scientific reports, 2020 - nature.com
Mutations in the SNX14 gene cause spinocerebellar ataxia, autosomal recessive 20 (SCAR20)
in both humans and dogs. Studies implicating the phenotypic consequences of SNX14 …
in both humans and dogs. Studies implicating the phenotypic consequences of SNX14 …
Three-dimensional imaging and single-cell transcriptomics of the human kidney implicate perturbation of lymphatics in alloimmunity
…, WJ Mason, BI Lee, L Heptinstall, G Pomeranz… - bioRxiv, 2022 - biorxiv.org
Studies of the structural and molecular features of the lymphatic vasculature, which clears
fluid, macromolecules and leukocytes from the tissue microenvironment, have largely relied on …
fluid, macromolecules and leukocytes from the tissue microenvironment, have largely relied on …
[HTML][HTML] Systemic gene therapy with thymosin β4 alleviates glomerular injury in mice
Plasma ultrafiltration in the kidney occurs across glomerular capillaries, which are surrounded
by epithelial cells called podocytes. Podocytes have a unique shape maintained by a …
by epithelial cells called podocytes. Podocytes have a unique shape maintained by a …
A unique subset of pericystic endothelium associates with aberrant microvascular remodelling and impaired blood perfusion early in polycystic kidney disease
DJ Jafree, C Perera, M Ball, D Tolomeo, G Pomeranz… - bioRxiv, 2024 - biorxiv.org
Hallmarks of autosomal dominant polycystic kidney disease (ADPKD), the most common
hereditary kidney anomaly, include expanding fluid-filled epithelial cysts, inflammation, and …
hereditary kidney anomaly, include expanding fluid-filled epithelial cysts, inflammation, and …
Exploration of the single-cell transcriptomic landscape identifies aberrant glomerular cell crosstalk in a murine model of WT1 kidney disease
JC Chandler, DJ Jafree, S Malik, G Pomeranz, M Ball… - bioRxiv, 2022 - biorxiv.org
The glomerulus mediates kidney ultrafiltration through specialised epithelial cells called
podocytes which line a basement membrane shared with blood capillary endothelium. Cell-cell …
podocytes which line a basement membrane shared with blood capillary endothelium. Cell-cell …
[PDF][PDF] Systemic gene therapy with thymosin b4 alleviates glomerular injury in mice
Results ADR is associated with the downregulation of TB4 in podocytes. ADR, a chemotherapeutic
drug, replicates some of the features of human focal segmental glomerulosclerosis (…
drug, replicates some of the features of human focal segmental glomerulosclerosis (…
# AskRenal: Use of an Automated Twitter Account to Crowdsource Nephrology Queries
JM Teakell, A Rosolowska, S Hiremath, MA Sparks… - 2022 - scholarlyworks.beaumont.org
Background: Social media platforms are used in contemporary crowdsourcing, and Twitter
is apt for reaching a large number of people with a common interest. Users, especially those …
is apt for reaching a large number of people with a common interest. Users, especially those …
ALVIS: interactive non-aggregative visualization and explorative analysis of multiple sequence alignments
RF Schwarz, AU Tamuri, M Kultys, J King… - Nucleic Acids …, 2016 - academic.oup.com
… We thank Joe Lau for implementation of the web interface, and Greg Slodkowicz, Gideon
Pomeranz and the participants of our user study for enthusiastic testing of the software. …
Pomeranz and the participants of our user study for enthusiastic testing of the software. …
Oral allergy syndrome (pollen-food allergy syndrome)
…, GP Smith, ML Stevenson, MK Pomeranz… - Dermatitis, 2015 - liebertpub.com
Oral allergy syndrome (OAS) or pollen-food allergy syndrome (PFS) is a hypersensitivity
reaction to plant-based foods, manifesting most commonly with pruritus of the lips, tongue, and …
reaction to plant-based foods, manifesting most commonly with pruritus of the lips, tongue, and …