[HTML][HTML] Structural determinants of antimicrobial and antiplasmodial activity and selectivity in histidine-rich amphipathic cationic peptides

…, A Marquette, P Shooshtarizaheh, G Moulay… - Journal of biological …, 2009 - ASBMB
Designed histidine-rich amphipathic cationic peptides, such as LAH4, have enhanced
membrane disruption and antibiotic properties when the peptide adopts an alignment parallel to …

Left atrial remodeling and atrioventricular coupling in a canine model of early heart failure with preserved ejection fraction

R Zakeri, G Moulay, Q Chai, O Ogut… - Circulation: Heart …, 2016 - Am Heart Assoc
Background— Left atrial (LA) compliance and contractility influence left ventricular stroke
volume. We hypothesized that diminished LA compliance and contractile function occur early …

Experimental cardiac radiation exposure induces ventricular diastolic dysfunction with preserved ejection fraction

H Saiki, G Moulay, AJ Guenzel, W Liu… - American Journal …, 2017 - journals.physiology.org
Breast cancer radiotherapy increases the risk of heart failure with preserved ejection
fraction (HFpEF). Cardiomyocytes are highly radioresistant, but radiation specifically affects …

Histidine‐rich designer peptides of the LAH4 family promote cell delivery of a multitude of cargo

G Moulay, C Leborgne, AJ Mason… - Journal of Peptide …, 2017 - Wiley Online Library
The histidine‐rich designer peptides of the LAH4 family exhibit potent antimicrobial, transfection,
transduction and cell‐penetrating properties. They form non‐covalent complexes with …

Optimising histidine rich peptides for efficient DNA delivery in the presence of serum

AJ Mason, C Leborgne, G Moulay, A Martinez… - Journal of controlled …, 2007 - Elsevier
We recently showed that the antibacterial histidine rich amphipathic peptide LAH4 has
significant DNA transfection capabilities in the absence of serum. To further understand the …

Clathrin plaques and associated actin anchor intermediate filaments in skeletal muscle

A Franck, J Lainé, G Moulay, E Lemerle… - Molecular biology of …, 2019 - Am Soc Cell Biol
Clathrin plaques are stable features of the plasma membrane observed in several cell types.
They are abundant in muscle, where they localize at costameres that link the contractile …

[HTML][HTML] Alternative splicing of clathrin heavy chain contributes to the switch from coated pits to plaques

G Moulay, J Lainé, M Lemaître, M Nakamori… - Journal of Cell …, 2020 - rupress.org
Clathrin function directly derives from its coat structure, and while endocytosis is mediated
by clathrin-coated pits, large plaques contribute to cell adhesion. Here, we show that the …

Membrane interaction of chrysophsin-1, a histidine-rich antimicrobial peptide from red sea bream

AJ Mason, P Bertani, G Moulay, A Marquette… - Biochemistry, 2007 - ACS Publications
Chrysophsin-1 is an amphipathic α-helical antimicrobial peptide produced in the gill cells of
red sea bream. The peptide has broad range activity against both Gram-positive and Gram-…

Caveolae and Bin1 form ring-shaped platforms for T-tubule initiation

E Lemerle, J Lainé, M Benoist, G Moulay, A Bigot… - Elife, 2023 - elifesciences.org
Excitation-contraction coupling requires a highly specialized membrane structure, the triad,
composed of a plasma membrane invagination, the T-tubule, surrounded by two …

[HTML][HTML] Cardiac AAV9 gene delivery strategies in adult canines: assessment by long-term serial SPECT imaging of sodium iodide symporter expression

G Moulay, T Ohtani, O Ogut, A Guenzel, A Behfar… - Molecular Therapy, 2015 - cell.com
Heart failure is a leading cause of morbidity and mortality, and cardiac gene delivery has
the potential to provide novel therapeutic approaches. Adeno-associated virus serotype 9 (…