Cytokinesis is a dynamic and plastic process involving the co-ordinated regulation of many
components. Accordingly, many proteins, including the putative scaffold protein anillin, …

The dual Rab11/Arf binding proteins, family of Rab11‐interacting proteins FIP3 and FIP4
function in the delivery of recycling endosomes to the cleavage furrow and are, together with …

Much of our understanding of animal cell cytokinesis centers on the regulation of the equatorial
acto-myosin contractile ring that drives the rapid ingression of a deep cleavage furrow [1–…

Cytokinesis requires a dramatic remodeling of the cortical cytoskeleton as well as membrane
addition. The Drosophila pericentrosomal protein, Nuclear-fallout (Nuf), provides a link …

Anillin is a conserved protein required for cytokinesis but its molecular function is unclear.
Anillin accumulation at the cleavage furrow is Rho guanine nucleotide exchange factor (GEF) …

… Well-established cell lines were used, all of which have been used in previously published
studies from the Baum and Hickson laboratories and their collaborators. Human cell lines …

Animal cell cytokinesis proceeds via constriction of an actomyosin-based contractile ring (CR)
[1, 2]. Upon reaching a diameter of ∼1 μm [3], a midbody ring (MR) forms to stabilize the …

Arfophilin is an ADP ribosylation factor (Arf) binding protein of unknown function. It is
identical to the Rab11 binding protein eferin/Rab11-FIP3, and we show it binds both Arf5 and …

During cytokinesis, closure of the actomyosin contractile ring (CR) is coupled to the
formation of a midbody ring (MR), through poorly understood mechanisms. Using time-lapse …

Background Animal cell cytokinesis is characterized by a sequence of dramatic cortical
rearrangements. How these are coordinated and coupled with mitosis is largely unknown. To …