Glycogen synthase kinase 3 (GSK3) is a critical enzyme in neuronal physiology; however, it
is not yet known whether it has any specific role in presynaptic function. We found that GSK3 …

Background Stem cell cultures are key tools of basic and applied research in Regenerative
Medicine. In the adult mammalian brain, lifelong neurogenesis originating from local …

The piriform cortex receives input from the olfactory bulb and (via the entorhinal cortex) sends
efferents to the hippocampus, thereby connecting the two canonical neurogenic regions of …

Background Following the severe acute respiratory syndrome (SARS) outbreak, remote-sensing
infrared thermography (IRT) has been advocated as a possible means of screening for …

Microglia, central nervous system (CNS) resident phagocytic cells, persistently police the
integrity of CNS tissue and respond to any kind of damage or pathophysiological changes. …

Bradykinin (BK) is produced and acts at the site of injury and inflammation. In the CNS, migration
of microglia toward the lesion site plays an important role pathologically. In the present …

Multiple synaptic vesicle (SV) retrieval modes exist in central nerve terminals to maintain a
continual supply of SVs for neurotransmission. Two such modes are clathrin-mediated …

Presynaptic glutamate replenishment is fundamental to brain function. In high activity
regimes, such as epileptic episodes, this process is thought to rely on the glutamate-glutamine …

Connexin hemichannels are single membrane channels which have been traditionally
thought to work in pairs to form gap junction channels across two opposing cells. In astrocytes, …

Local translation is a conserved mechanism conferring cells the ability to quickly respond to
local stimuli. In the brain, it has been recently reported in astrocytes, whose fine processes …