User profiles for Giulio Bernardinelli

Giulio Bernardinelli

Karolinska Institutet
Verified email at ki.se
Cited by 173

Interplay of Three G-Quadruplex Units in the KIT Promoter

C Ducani, G Bernardinelli, B Högberg… - Journal of the …, 2019 - ACS Publications
The proto-oncogene KIT encodes for a tyrosine kinase receptor, which is a clinically
validated target for treating gastrointestinal stromal tumors. The KIT promoter contains a G-rich …

Entirely enzymatic nanofabrication of DNA–protein conjugates

G Bernardinelli, B Högberg - Nucleic Acids Research, 2017 - academic.oup.com
While proteins are highly biochemically competent, DNA offers the ability to program, both
reactions and the assembly of nanostructures, with a control that is unprecedented by any …

[PDF][PDF] A DNA nanoassembly-based approach to map membrane protein nanoenvironments

E Ambrosetti, G Bernardinelli, IT Hoffecker… - Biophysical …, 2021 - cell.com
Institutet, Stockholm, Sweden, 3Laboratory for Environmental and Life Sciences, University
of Nova Gorica, Nova Gorica, Slovenia. Super-resolution imaging has revealed that most …

Rolling circle replication requires single-stranded DNA binding protein to avoid termination and production of double-stranded DNA

C Ducani, G Bernardinelli, B Högberg - Nucleic Acids Research, 2014 - academic.oup.com
In rolling circle replication, a circular template of DNA is replicated as a long single-stranded
DNA concatamer that spools off when a strand displacing polymerase traverses the circular …

A computational framework for DNA sequencing microscopy

IT Hoffecker, Y Yang, G Bernardinelli… - Proceedings of the …, 2019 - National Acad Sciences
We describe a method whereby microscale spatial information such as the relative positions
of biomolecules on a surface can be transferred to a sequence-based format and …

A compact nanobody-DNAzyme conjugate enables antigen detection and signal amplification

G Bernardinelli, S Oloketuyi, SF Werner, E Mazzega… - New biotechnology, 2020 - Elsevier
Hemin-utilizing G-quadruplex DNAzymes with peroxidase-like (POX) activity are widely
used as signal reporters in biosensing technology. However, their application to protein …

[PDF][PDF] Reconstructing Nanoscale Structures from Sequence Topology of Spatial Networks of Barcoded DNA

IT Hoffecker, G Bernardinelli, L Vornholz, Y Yang… - Biophysical …, 2018 - cell.com
692a Wednesday, February 21, 2018 electron microscopy, however such methods often
lack throughput and the statistical power needed to characterize populations of cells or …

A computational framework for DNA sequencing-based microscopy

IT Hoffecker, Y Yang, G Bernardinelli, P Orponen… - bioRxiv, 2018 - biorxiv.org
Barcoded DNA polony amplification techniques provide a means to impart a unique sequence
identity onto specific locations of a surface wafer or chip. We describe a method whereby …

Single-Stranded DNA: Methods and Application in Nanotechnology

G Bernardinelli - 2019 - search.proquest.com
Basic molecular and cell research, production of recombinant proteins, diagnostic detection
of genetic mutations, construction of nanostructures and high-throughput DNA sequencing …

[CITATION][C] Nanobody Engineering Provides Diagnostic Reagents For The Quantification Of The Toxic Microalgae Alexandrium minutum

…, S Oloketuyi, G Bernardinelli… - 1st Bonn Nanobody …, 2019 - repozitorij.ung.si
Bernardinelli, Giulio, Karolinska Instituet (Avtor) …