User profiles for Giulio Giuliani

Giulio Giuliani

Institute of Biochemistry II, Goethe-Universität Frankfurt am Main
Verified email at med.uni-frankfurt.de
Cited by 297

Signaling pathways regulating the fate of fibro/adipogenic progenitors (FAPs) in skeletal muscle regeneration and disease

G Giuliani, M Rosina, A Reggio - The FEBS journal, 2022 - Wiley Online Library
The characterization of fibro/adipogenic progenitor cells (FAPs) in the skeletal muscle has
contributed to modify the monocentric view of muscle regeneration beyond muscle satellite …

Adipogenesis of skeletal muscle fibro/adipogenic progenitors is affected by the WNT5a/GSK3/β-catenin axis

…, C Gargioli, C Fuoco, E Micarelli, G Giuliani… - Cell Death & …, 2020 - nature.com
Fibro/Adipogenic Progenitors (FAPs) are muscle-interstitial progenitors mediating pro-myogenic
signals that are critical for muscle homeostasis and regeneration. In myopathies, the …

Fibro-adipogenic progenitors of dystrophic mice are insensitive to NOTCH regulation of adipogenesis

…, F Sacco, AC Perpetuini, G Giuliani… - Life Science …, 2019 - life-science-alliance.org
Fibro-adipogenic progenitors (FAPs) promote satellite cell differentiation in adult skeletal
muscle regeneration. However, in pathological conditions, FAPs are responsible for fibrosis …

[HTML][HTML] SCA-1 micro-heterogeneity in the fate decision of dystrophic fibro/adipogenic progenitors

G Giuliani, S Vumbaca, C Fuoco, C Gargioli… - Cell Death & …, 2021 - nature.com
The term micro-heterogeneity refers to non-genetic cell to cell variability observed in a bell-shaped
distribution of the expression of a trait within a population. The contribution of micro-…

[HTML][HTML] Characterization of the skeletal muscle secretome reveals a role for extracellular vesicles and IL1α/IL1β in restricting fibro/adipogenic progenitor adipogenesis

S Vumbaca, G Giuliani, V Fiorentini, F Tortolici… - Biomolecules, 2021 - mdpi.com
Repeated mechanical stress causes injuries in the adult skeletal muscle that need to be
repaired. Although muscle regeneration is a highly efficient process, it fails in some pathological …

[HTML][HTML] Janus effect of glucocorticoids on differentiation of muscle fibro/adipogenic progenitors

A Cerquone Perpetuini, G Giuliani, A Reggio… - Scientific Reports, 2020 - nature.com
Muscle resident fibro-adipogenic progenitors (FAPs), support muscle regeneration by
releasing cytokines that stimulate the differentiation of myogenic stem cells. However, in non-…

Graphene nanoribbons are internalized by human primary immune cell subpopulations maintaining a safety profile: A high-dimensional pilot study by single-cell mass …

C Fuoco, X Luan, L Fusco, F Riccio, G Giuliani… - Applied Materials …, 2022 - Elsevier
Graphene nanoribbons (GNRs) are emerging graphene materials showing clear promising
applications in the biomedical field. The evaluation of GNR biocompatibility at the immune …

[HTML][HTML] A resource for the network representation of cell perturbations caused by SARS-CoV-2 infection

…, E Micarelli, M Iannuccelli, P Lo Surdo, G Giuliani… - Genes, 2021 - mdpi.com
The coronavirus disease 2019 (COVID-19) pandemic has caused more than 2.3 million
casualties worldwide and the lack of effective treatments is a major health concern. The …

[HTML][HTML] Skeletal muscle subpopulation rearrangements upon rhabdomyosarcoma development through single-cell mass cytometry

LL Petrilli, F Riccio, G Giuliani, A Palma… - Journal of Clinical …, 2021 - mdpi.com
The embryonal rhabdomyosarcoma (eRMS) is a soft tissue sarcoma commonly affecting the
head and neck, the extremities and the genitourinary tract. To contribute to revealing the cell …

[HTML][HTML] Myo-REG: A portal for signaling interactions in muscle regeneration

…, F Ferrentino, C Fuoco, C Gargioli, G Giuliani… - Frontiers in …, 2019 - frontiersin.org
Muscle regeneration is a complex process governed by the interplay between several
muscle-resident mononuclear cell populations. Following acute or chronic damage these cell …