Recently, the ability of natural phospholipids to self-assemble into organized membrane-enclosed
structures has been mimicked by amphiphilic copolymers.[1, 2] These synthetic …

Unilamellar polymer vesicles are formed when a block copolymer self-assembles to form a
single bilayer structure, with a hydrophobic core and hydrophilic surfaces, and the resulting …

Functionalized drug delivery systems against malignant lung metastasis of breast cancer
have been extensively studied, while metastasis remains a challenging issue. We propose a …

Background Patients with reflux esophagitis have a high rate of relapse within one year after
therapy is discontinued. Methods We enrolled 175 adults with endoscopy-confirmed reflux …

The worldwide spread of COVID-19 has upset the normality of Italian daily life, forcing population
to social distancing and self-isolation. Since the containment precautions also concern …

Background Intermittent fasting (IF) is an increasingly popular dietary approach used for
weight loss and overall health. While there is an increasing body of evidence demonstrating …

Endocytosis is a fundamental process in which eukaryotic cells internalise molecules and
macromolecules via deformation of the membrane and generation of membrane-bound …

Amphiphilic diblock copolymers composed of two covalently linked, chemically distinct chains
can be considered to be biological mimics of cell membrane-forming lipid molecules, but …

In animals, sporadic injections of the mitochondrial toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
(MPTP) selectively damage dopaminergic neurons but do not fully reproduce the …

An abundant presynaptic protein, α-synuclein, is centrally involved in the pathogenesis of
Parkinson's disease. However, conflicting data exist about the normal function of α-synuclein, …