Leucine-rich repeat (LRR) proteins have recently been identified as important regulators of
synapse development and function, but for many LRR proteins the ligand-receptor …

Leukocyte common antigen-related receptor protein tyrosine phosphatases—comprising LAR,
PTPδ, and PTPσ—are synaptic adhesion molecules that organize synapse development. …

Neural circuits consist of distinct neuronal cell types connected in specific patterns. The
specificity of these connections is achieved in a series of sequential developmental steps that …

The endoplasmic reticulum (ER) is a large, multifunctional and essential organelle. Despite
intense research, the function of more than a third of ER proteins remains unknown even in …

Pyramidal neuron dendrites integrate synaptic input from multiple partners. Different inputs
converging on the same dendrite have distinct structural and functional features, but the …

Establishing synaptic contacts between neurons is paramount for nervous system function.
This process involves transsynaptic interactions between a host of cell adhesion molecules …

Excitatory and inhibitory neurons are connected into microcircuits that generate circuit output.
Central in the hippocampal CA3 microcircuit is the mossy fiber (MF) synapse, which …

Glioblastomas are the most frequent and aggressive intracranial neoplasms in humans, and
despite advances and the introduction of the alkylating agent temozolomide in therapy have …

In the mammalian neocortex, excitatory pyramidal cells are assembled into distinct subnetworks,
which project to different brain areas. GABAergic interneurons were long thought to …

… Smukowski3, Jeroen Vanderlinden1,2, Giuseppe Condomitti1,2, Vasily Rybakin4, Jolijn
ten Bos1,2, Sybren Portegies1,2, Kristel M. Vennekens1,2, Natalia V. Gounko1,2,5, Keimpe …