User profiles for Gladden-Young A.
Adrianne Gladden-YoungBroad Institute of MIT and Harvard Verified email at broadinstitute.org Cited by 6190 |
Virus genomes reveal factors that spread and sustained the Ebola epidemic
…, ML Gilbert, SM Gevao, S Gire, A Gladden-Young… - Nature, 2017 - nature.com
The 2013–2016 West African epidemic caused by the Ebola virus was of unprecedented
magnitude, duration and impact. Here we reconstruct the dispersal, proliferation and decline of …
magnitude, duration and impact. Here we reconstruct the dispersal, proliferation and decline of …
Zika virus evolution and spread in the Americas
…, K West, J Qu, ML Baniecki, A Gladden-Young… - Nature, 2017 - nature.com
Although the recent Zika virus (ZIKV) epidemic in the Americas and its link to birth defects
have attracted a great deal of attention 1 , 2 , much remains unknown about ZIKV disease …
have attracted a great deal of attention 1 , 2 , much remains unknown about ZIKV disease …
Phylogenetic analysis of SARS-CoV-2 in Boston highlights the impact of superspreading events
INTRODUCTION We used genomic epidemiology to investigate the introduction and spread
of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the Boston area …
of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the Boston area …
[HTML][HTML] Ebola virus epidemiology, transmission, and evolution during seven months in Sierra Leone
…, SM Winnicki, J Qu, SK Gire, A Gladden-Young… - Cell, 2015 - cell.com
The 2013–2015 Ebola virus disease (EVD) epidemic is caused by the Makona variant of
Ebola virus (EBOV). Early in the epidemic, genome sequencing provided insights into virus …
Ebola virus (EBOV). Early in the epidemic, genome sequencing provided insights into virus …
Genomic epidemiology reveals multiple introductions of Zika virus into the United States
Zika virus (ZIKV) is causing an unprecedented epidemic linked to severe congenital abnormalities
1 , 2 . In July 2016, mosquito-borne ZIKV transmission was reported in the continental …
1 , 2 . In July 2016, mosquito-borne ZIKV transmission was reported in the continental …
[HTML][HTML] Genomic analysis of Lassa virus during an increase in cases in Nigeria in 2018
…, D Kotliar, A Carter, A Gladden-Young… - … England Journal of …, 2018 - Mass Medical Soc
During 2018, an unusual increase in Lassa fever cases occurred in Nigeria, raising concern
among national and international public health agencies. We analyzed 220 Lassa virus …
among national and international public health agencies. We analyzed 220 Lassa virus …
MYB-QKI rearrangements in angiocentric glioma drive tumorigenicity through a tripartite mechanism
Angiocentric gliomas are pediatric low-grade gliomas (PLGGs) without known recurrent
genetic drivers. We performed genomic analysis of new and published data from 249 PLGGs, …
genetic drivers. We performed genomic analysis of new and published data from 249 PLGGs, …
[HTML][HTML] Capturing sequence diversity in metagenomes with comprehensive and scalable probe design
Metagenomic sequencing has the potential to transform microbial detection and
characterization, but new tools are needed to improve its sensitivity. Here we present CATCH, a …
characterization, but new tools are needed to improve its sensitivity. Here we present CATCH, a …
Direct characterization of cis-regulatory elements and functional dissection of complex genetic associations using HCR–FlowFISH
…, D Berenzy, S Kales, GM Butler, A Gladden-Young… - Nature …, 2021 - nature.com
Effective interpretation of genome function and genetic variation requires a shift from epigenetic
mapping of cis-regulatory elements (CREs) to characterization of endogenous function. …
mapping of cis-regulatory elements (CREs) to characterization of endogenous function. …
[HTML][HTML] Phylogenetic analysis of SARS-CoV-2 in the Boston area highlights the role of recurrent importation and superspreading events.
SARS-CoV-2 has caused a severe, ongoing outbreak of COVID-19 in Massachusetts with
111,070 confirmed cases and 8,433 deaths as of August 1, 2020. To investigate the …
111,070 confirmed cases and 8,433 deaths as of August 1, 2020. To investigate the …